Results 51 to 60 of about 115,466 (314)
Advanced Science, EarlyView.Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu +12 more
wiley +1 more source
Three in one: evolution of viviparity, coenocytic placenta and polyembryony in cyclostome bryozoans
BMC Ecology and Evolution, 2021 Background Placentation has evolved multiple times among both chordates and invertebrates. Although they are structurally less complex, invertebrate placentae are much more diverse in their origin, development and position.
U. A. Nekliudova +5 more
doaj +1 more source
Biology and Life Sciences Forum, 2023 Breast cancer is the most prevalent cancer in the female population. The prolonged action of estrogen may affect tumor proliferation. Additionally, a fat-rich diet may have various effects on cancer proliferation, depending on the type of fat. Vitamin D,
Kamila Sobczak +6 more
doaj +1 more source
Ultrastructure of a craniopharyngioma [PDF]
Cancer, 1971 A craniopharyngioma removed at surgery was examined by light and electron microscopy. The tumor consisted of both solid and cystic components. The cells lining the cysts, as well as those forming the solid masses, displayed desmosomes, tonofilaments, keratohyalin granules, and keratinization identical to those seen in the epidermis.
N R, Ghatak, A, Hirano, H M, Zimmerman
openaire +2 more sources
A 3D In Vitro Model of the Human Hepatobiliary Junction
Advanced Science, EarlyView.A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield +13 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyBackgroundThe protozoan Leishmania, in addition to infecting phagocytic cells such as macrophages, can also invade non-professional phagocytic cells like fibroblasts, a process previously described in 2D models.
Rebecca Thereza Silva Santa Brígida +7 more
doaj +1 more source
The better to eat you with: morphological disparity and enamel ultrastructure in odontocetes
Scientific Reports, 2023 Variations in the shape and size of teeth have been associated with changes in enamel ultrastructure across odontocetes. Characterizing these features in extinct taxa can elucidate their functional morphology and feeding strategy, while also shedding ...
Mariana Viglino +3 more
doaj +1 more source
Advanced Science, EarlyView.We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha +13 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source