Results 151 to 160 of about 408,744 (292)

A Fluorogenic Cysteine‐Tetrapeptide Tagging Strategy for Nonperturbative Protein Labeling and Protein–Ligand Interaction Tracking

open access: yesAdvanced Science, EarlyView.
A compact Phe‐Cys‐Pro‐Phe (FCPF) tag and an environment‐sensitive SBD‐Cl‐derived probe form a sequence‐selective fluorogenic pair for wash‐free live‐cell protein imaging. This minimally perturbing chemistry allows flexible insertion at termini or loops, produces strong fluorescence upon local microenvironment confinement, supports FRET‐assisted ...
Xiao Wang   +11 more
wiley   +1 more source

A Precision‐Delivered Singlet Oxygen Generator With an Inbuilt Safety Switch for Induction of Pancreatic Beta Cell Stress and Death

open access: yesAngewandte Chemie, EarlyView.
ROXendin668 is a peptidic GLP‐1 receptor agonist that generates toxic singlet oxygen upon irradiation with far‐red light. Pancreatic beta cells can be photo‐ablated in a spatiotemporally controlled manner. This approach has the potential to provide a safer alternative to streptozotocin or alloxan for creating model systems for type 1 diabetes research.
Kilian Roßmann   +17 more
wiley   +2 more sources

Homotopy Perturbation Method for Investigating Population Dynamics in Oxygen-Depleted Environments

open access: yesDiscrete Dynamics in Nature and Society
This research will seek to construct a theoretical model to study both the ultraviolet (UV) degradation of hydrogen sulfide (H2S) without oxygen and population dynamics in anoxic environments. Solving some of the issues in biogas energy usage, this paper
V. Sreelatha Devi   +3 more
doaj   +1 more source

Water‐Coupled Interfacial Modulation Enhances Photovoltaic and Pyroelectric Responses in Transparent Self‐Powered ZnO/NiO Photodetectors

open access: yesAdvanced Science, EarlyView.
Direct water contact enhances the performance of a transparent self‐powered FTO/ZnO/NiO/AgNW/ZnO UV photodetector. Reduced surface reflection improves optical transmission, while an electric double layer at the ZnO/water interface modulates interfacial electrostatics and promotes charge separation.
Seunghee Cho   +6 more
wiley   +1 more source

Conformationally Switchable Copper(I) Complexes Amplify BODIPY Triplet Photosensitization

open access: yesAngewandte Chemie, EarlyView.
Coupling a structurally switchable Cu(I) complex to an organic light‐harvesting chromophore boosts photoinduced intersystem crossing via the transient formation of a Cu(II) intermediate. Spectroscopic, physical, computational, and photocatalytic studies support this unique new approach to solar energy upconversion.
Nisha Kamboj   +4 more
wiley   +2 more sources

Metasurface‐Based Multidimensional Light‐Field Manipulation: From Technologies to Applications

open access: yesAdvanced Science, EarlyView.
Multidimensional metasurfaces enable versatile manipulation of multiple optical degrees of freedom, including phase, amplitude, polarization, wavelength, and orbital angular momentum. This review summarizes their fundamental mechanisms, emerging strategies for multidimensional light‐field control, and key applications in optical computing, imaging ...
Heliang Yin   +6 more
wiley   +1 more source

Efficient Green Light‐Induced Photoclick Reactions Enabled by Triplet–Triplet Annihilation Photon Upconversion

open access: yesAngewandte Chemie, EarlyView.
A general strategy for 9,10‐phenanthrenequinone‐electron‐rich alkene (PQ‐ERA) photoclick reactions via triplet–triplet annihilation upconversion (TTA‐UC) under low‐intensity green light is reported. A TTA‐UC system of PdOEP (sensitizer) and DPA (annihilator) mixed with reactants generates UV/blue photons overlapping the absorption of PQ derivatives ...
Qingxin Luan   +7 more
wiley   +2 more sources

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

Probing Dust Composition in Distant Galaxies with JWST Mid-IR Spectroscopy of Quasars with Foreground 2175 Å Absorbers. II. Measurements of Grain Composition and Extinction Properties

open access: yesThe Astrophysical Journal
We present results from a mini-survey of dust spectral features arising in galaxies at redshifts 0.5 
Viacheslav V. Klimenko   +2 more
doaj   +1 more source

The potential and pitfalls of de-extinction

open access: yes, 2016
‘De-extinction’ is the nascent discipline that aims to one day literally revive now-extinct species from the dead. Although we have yet to see any successful attempts to truly resurrect an extinct species, several technologies are now in place that might
D. Richmond (23399908)   +2 more
core  

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