Results 61 to 70 of about 155,033 (349)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Upcoming Therapeutic Modalities for the Treatment of Keloids: An Update

open access: yesNepal Journal of Dermatology, Venereology & Leprology, 2019
Introduction: Keloids are benign dermal tumors that generally form by local fibroblast proliferation and excessive collagen production following skin trauma.
Uma Keyal, Anil Kumar Bhatta
doaj   +3 more sources

Fashionitis: Can the colours we wear affect our health [PDF]

open access: yes, 2009
Colour therapy is a popular ancient healing art that makes use of colour vibrational energies to balance and harmonise the body’s subtle energies and physical organs in order to create a state of holistic well-being and good health.
Cassidy, Tracy Diane
core  

WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway [PDF]

open access: yes, 2015
Stress exposure triggers ligand-independent EGF receptor (EGFR) endocytosis, but its post-endocytic fate and role in regulating signalling are unclear. We show that the p38 MAP kinase-dependent, EGFR tyrosine kinase (TK)-independent EGFR internalization ...
Burgoyne, T   +6 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. [PDF]

open access: yes, 2016
BackgroundPUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of ...
Abrouk, Michael   +10 more
core   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Ultraviolet A Is AnEfficient Therapy For Plane Warts

open access: yesDiyala Journal of Medicine, 2019
Background:Treatment ofplane warts presents a special therapeutic problem because their duration is long, and very resistant to many treatments. In addition they are usually located in cosmetically important areas, so therapy should be as mild as ...
AlaaAldeen Khorsheed Murad   +2 more
doaj   +2 more sources

Generalized syringotropic mycosis fungoides responsive to total skin electron beam therapy

open access: yesDermatologica Sinica, 2014
A case of syringotropic mycosis fungoides without internal organ involvement received total skin electron beam therapy (TSEBT) and evolved into poikilodermatous mycosis fungoides.
Pei-Hsuan Lu   +4 more
doaj   +1 more source

Evaluation of non-endemic pemphigus foliaceus in a large series of patients: a single-center retrospective study from Turkey focuses on the relapses

open access: yesAnais Brasileiros de Dermatologia, 2021
Background: Pemphigus foliaceus is exceedingly rare around the world, except within the few regions where it occurs as an endemic variant. Various factors can trigger immune mechanisms that induce pemphigus foliaceus or worsen its course.
Sıla Kılıç Sayar   +1 more
doaj   +1 more source

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