Results 11 to 20 of about 1,187 (117)

The antitumor activity of umbelliferone in human renal cell carcinoma via regulation of the p110γ catalytic subunit of PI3Kγ [PDF]

open access: yesActa Pharmaceutica, 2019
Umbelliferone exhibits extensive pharmacological activity, including anti-immunomodulatory, anti-inflammatory and antigenotoxicity activities. However, its antitumor properties still remain unclear in human renal cell carcinoma (RCC) cells.
Wang Xue   +5 more
doaj   +3 more sources

Synthesis of umbelliferone derivatives in Escherichia coli and their biological activities

open access: yesJournal of Biological Engineering, 2017
Background Umbelliferone, also known as 7-hydroxycoumarin, is a phenolic metabolite found in many familiar plants. Its derivatives have been shown to have various pharmacological and chemo-preventive effects on human health.
Luan Luong Chu   +6 more
doaj   +2 more sources

Promising Fungicides from Allelochemicals: Synthesis of Umbelliferone Derivatives and Their Structure–Activity Relationships

open access: yesMolecules, 2018
Umbelliferone was discovered to be an important allelochemical in our previous study, but the contribution of its activity and structure has not yet been revealed.
Le Pan   +4 more
doaj   +2 more sources

Umbelliferone presents orofacial antinociceptive and anti-inflammatory activity via reduction of TNF-α in mice [PDF]

open access: yesBrazilian Journal of Biology
Pain is a normal response of the central nervous system to trauma, infections, neoplasms, neuropathies, and inflammation. It can arise from physical, emotional, or cognitive conditions, and is classified as orofacial pain when it affects the mouth and ...
P. N. S. Silva   +10 more
doaj   +3 more sources

Data on efficacy of umbelliferone on glycoconjugates and immunological marker in 7,12-dimethylbenz(a)anthracene induced oral carcinogenesis

open access: yesData in Brief, 2017
Umbelliferone, a phenolic coumarin and dietary agent is believed to play a key role in pharmacological activities including anti-cancer and anti-oxidants effect in various in vitro and in vivo models. In present data on the pre-treatment of umbelliferone
Annamalai Vijayalakshmi   +1 more
doaj   +2 more sources

MICROWAVE-ASSISTED SYNTHESIS AND PKA DETERMINATION OF UMBELLIFERONE: AN EXPERIMENT FOR THE UNDERGRADUATE ORGANIC CHEMISTRY LABORATORY

open access: yesQuímica Nova
A synthetic procedure for obtaining the fluorescent coumarin umbelliferone (7-hydroxycoumarin) and its spectral parameters were fully developed aiming at an undergraduate organic chemistry laboratory class.
Thiago M. Pereira   +5 more
doaj   +2 more sources

Separation and identification of antibacterial chamomile components using OPLC, bioautography and GC-MS [PDF]

open access: yes, 2012
Components of 50% ethanolic chamomile (Matricaria recutica L.) flower extract, previously found antibacterial in a TLC-bioautographic study, were separated and isolated by the use of on-line OPLC, which consisted of an OPLC 50 BS system, an on-line ...
Móricz, Ágnes M.   +5 more
core   +1 more source

Investigation of the Chemical Composition, Antihyperglycemic and Antilipidemic Effects of Bassia eriophora and Its Derived Constituent, Umbelliferone on High-Fat Diet and Streptozotocin-Induced Diabetic Rats

open access: yesMolecules, 2022
This study was designed to investigate the chemical profile, antihyperglycemic and antilipidemic effect of total methanolic extract (TME) of Bassia eriophora and isolated pure compound umbelliferone (UFN) in high-fat diet (HFD)- and streptozotocin (STZ)-
Abdulaziz K. Al Mouslem   +3 more
doaj   +1 more source

Comparison of various techniques for the extraction of umbelliferone and herniarin in Matricaria chamomilla processing fractions

open access: yesChemistry Central Journal, 2017
Chamomile, a well-known medicinal plant, is a rich source of bioactive compounds, among which two coumarin derivatives, umbelliferone and herniarin, are often found in its extracts.
Maja Molnar   +4 more
doaj   +1 more source

Natural Drug-Loaded Bimetal-Substituted Hydroxyapatite-Polymeric Composite for Osteosarcoma-Affected Bone Repair

open access: yesFrontiers in Cell and Developmental Biology, 2021
Repairing segmental bone deformities after resection of dangerous bone tumors is a long-standing clinical issue. The study’s main objective is to synthesize a natural bioactive compound-loaded bimetal-substituted hydroxyapatite (BM-HA)-based composite ...
Yanjun Wang   +6 more
doaj   +1 more source

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