Results 11 to 20 of about 4,051 (210)

Umbelliferone: Sources, chemistry and bioactivities review

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2017
Umbelliferone is a 7-hydroxycoumarin that is a pharmacologically active agent. It is widely distributed within the Rutaceae and Apiaceae (Umbelliferae) families and is efficiently extracted using methanol.
Ofentse Mazimba
doaj   +3 more sources

Synthesis of umbelliferone derivatives in Escherichia coli and their biological activities [PDF]

open access: yesJournal of Biological Engineering, 2017
Background Umbelliferone, also known as 7-hydroxycoumarin, is a phenolic metabolite found in many familiar plants. Its derivatives have been shown to have various pharmacological and chemo-preventive effects on human health.
Luan Luong Chu   +6 more
doaj   +5 more sources

The antitumor activity of umbelliferone in human renal cell carcinoma via regulation of the p110γ catalytic subunit of PI3Kγ

open access: yesActa Pharmaceutica, 2019
Umbelliferone exhibits extensive pharmacological activity, including anti-immunomodulatory, anti-inflammatory and antigenotoxicity activities. However, its antitumor properties still remain unclear in human renal cell carcinoma (RCC) cells.
Wang Xue   +5 more
doaj   +3 more sources

Twice as Nice: The Duff Formylation of Umbelliferone Revised [PDF]

open access: yesMolecules, 2021
More efficient and preferably more convenient and greener synthetic solutions in coumarin scaffold functionalization are in steady demand. The Duff ortho-formylation of unsubstituted umbelliferone was revised in this study. The reaction conditions were optimized based upon data from the literature analysis and resulted in unexpectedly rapid ortho ...
Vladislav V. Skarga   +3 more
openaire   +4 more sources

Promising Fungicides from Allelochemicals: Synthesis of Umbelliferone Derivatives and Their Structure–Activity Relationships

open access: yesMolecules, 2018
Umbelliferone was discovered to be an important allelochemical in our previous study, but the contribution of its activity and structure has not yet been revealed.
Le Pan   +4 more
doaj   +2 more sources

Umbelliferone presents orofacial antinociceptive and anti-inflammatory activity via reduction of TNF-α in mice [PDF]

open access: yesBrazilian Journal of Biology
Pain is a normal response of the central nervous system to trauma, infections, neoplasms, neuropathies, and inflammation. It can arise from physical, emotional, or cognitive conditions, and is classified as orofacial pain when it affects the mouth and ...
P. N. S. Silva   +10 more
doaj   +2 more sources

Data on efficacy of umbelliferone on glycoconjugates and immunological marker in 7,12-dimethylbenz(a)anthracene induced oral carcinogenesis

open access: yesData in Brief, 2017
Umbelliferone, a phenolic coumarin and dietary agent is believed to play a key role in pharmacological activities including anti-cancer and anti-oxidants effect in various in vitro and in vivo models. In present data on the pre-treatment of umbelliferone
Annamalai Vijayalakshmi   +1 more
doaj   +2 more sources

Fluorescence of some simple umbelliferone derivatives

open access: yesCollection of Czechoslovak Chemical Communications, 1979
The absorption and fluorescence spectra of umbelliferone were studied; it was found that in the excited state the basicity of the α-pyrone part of the molecule increases to such an extent that it exceeds that of the phenolate oxygen of the molecule. This is responsible for the neutral nondissociated form of umbelliferone being only in nonpolar medium ...
Vladimír Mikeš
openaire   +2 more sources

MICROWAVE-ASSISTED SYNTHESIS AND PKA DETERMINATION OF UMBELLIFERONE: AN EXPERIMENT FOR THE UNDERGRADUATE ORGANIC CHEMISTRY LABORATORY

open access: yesQuímica Nova
A synthetic procedure for obtaining the fluorescent coumarin umbelliferone (7-hydroxycoumarin) and its spectral parameters were fully developed aiming at an undergraduate organic chemistry laboratory class.
Thiago M. Pereira   +5 more
doaj   +2 more sources

Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives [PDF]

open access: yesMolecules, 2020
Coumarin derivatives are a class of compounds with a pronounced wide range of applications, especially in biological activities, in the medicine, pharmacology, cosmetics, coatings and food industry. Their potential applications are highly dependent on the nature of the substituents attached to their nucleus.
Rubén Seoane-Rivero   +8 more
openaire   +5 more sources

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