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Umbelliferone: Sources, chemistry and bioactivities review
Umbelliferone is a 7-hydroxycoumarin that is a pharmacologically active agent. It is widely distributed within the Rutaceae and Apiaceae (Umbelliferae) families and is efficiently extracted using methanol.
Ofentse Mazimba
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Synthesis of umbelliferone derivatives in Escherichia coli and their biological activities [PDF]
Background Umbelliferone, also known as 7-hydroxycoumarin, is a phenolic metabolite found in many familiar plants. Its derivatives have been shown to have various pharmacological and chemo-preventive effects on human health.
Luan Luong Chu +6 more
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Twice as Nice: The Duff Formylation of Umbelliferone Revised [PDF]
More efficient and preferably more convenient and greener synthetic solutions in coumarin scaffold functionalization are in steady demand. The Duff ortho-formylation of unsubstituted umbelliferone was revised in this study. The reaction conditions were optimized based upon data from the literature analysis and resulted in unexpectedly rapid ortho ...
Vladislav V. Skarga +3 more
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Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives [PDF]
Coumarin derivatives are a class of compounds with a pronounced wide range of applications, especially in biological activities, in the medicine, pharmacology, cosmetics, coatings and food industry. Their potential applications are highly dependent on the nature of the substituents attached to their nucleus.
Rubén Seoane-Rivero +8 more
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Repairing segmental bone deformities after resection of dangerous bone tumors is a long-standing clinical issue. The study’s main objective is to synthesize a natural bioactive compound-loaded bimetal-substituted hydroxyapatite (BM-HA)-based composite ...
Yanjun Wang +6 more
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Zur Kenntniss des Umbelliferons [PDF]
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Will, W., Beck, P.
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Two known coumarins, scopoletin (SP) and umbelliferone (UB), were isolated from Cortex Mori (CM). Their structures were elucidated by various spectroscopic analyses.
Yijun Liang +7 more
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Chamomile, a well-known medicinal plant, is a rich source of bioactive compounds, among which two coumarin derivatives, umbelliferone and herniarin, are often found in its extracts.
Maja Molnar +4 more
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Antifungal activity of davanone-type sesquiterpenes from Artemisia lobelli var. conescens [PDF]
Five tetrahydrofuran sesquiterpenes, so-called davanones, and coumarin umbelliferone isolated from Artemisia lobelii All. var. canescens (DC) Briqu, were tested for antifungal activity. All the compounds inhibited the growth of the applied fungi.
Vajs Vlatka +5 more
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Umbelliferone exhibits extensive pharmacological activity, including anti-immunomodulatory, anti-inflammatory and antigenotoxicity activities. However, its antitumor properties still remain unclear in human renal cell carcinoma (RCC) cells.
Wang Xue +5 more
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