Results 21 to 30 of about 3,798 (181)

Promising Fungicides from Allelochemicals: Synthesis of Umbelliferone Derivatives and Their Structure–Activity Relationships

Molecules, 2018
Umbelliferone was discovered to be an important allelochemical in our previous study, but the contribution of its activity and structure has not yet been revealed.
Le Pan, Dongyu Lei, Lu Jin, Yuan He, Qingqing Yang   +4 more
doaj   +1 more source

Proteomic profiling spotlights the molecular targets and the impact of the natural antivirulent umbelliferone on stress response, virulence factors, and the quorum sensing network of Pseudomonas aeruginosa

Frontiers in Cellular and Infection Microbiology, 2022
Pseudomonas aeruginosa easily adapts to newer environments and acquires several genome flexibilities to overcome the effect of antibiotics during therapeutics, especially in cystic fibrosis patients.
Thirupathi Kasthuri, Sivaraj Barath, Muruganandam Nandhakumar, Shunmugiah Karutha Pandian   +3 more
doaj   +1 more source

Elucidation of the biosynthesis pathway and heterologous construction of a sustainable route for producing umbelliferone

Journal of Biological Engineering, 2019
Background Coumarins play roles in many biological processes. Angelica decursiva is one of the major sources of coumarins in China. Due to increasing demand for coumarins in the marketplace, traditional extraction from plants is now considered ...
Yucheng Zhao, Xiangyun Jian, Jialin Wu, Wanchun Huang, Chuanlong Huang, Jun Luo, Lingyi Kong   +6 more
doaj   +1 more source

Antiglioma Potential of Coumarins Combined with Sorafenib

Molecules, 2020
Coumarins, which occur naturally in the plant kingdom, are diverse class of secondary metabolites. With their antiproliferative, chemopreventive and antiangiogenetic properties, they can be used in the treatment of cancer.
Joanna Sumorek-Wiadro, Adrian Zając, Ewa Langner, Krystyna Skalicka-Woźniak, Aleksandra Maciejczyk, Wojciech Rzeski, Joanna Jakubowicz-Gil   +6 more
doaj   +1 more source

Coumarin: a novel player in microbial quorum sensing and biofilm formation inhibition [PDF]

, 2018
Antibiotic resistance is a growing threat worldwide, causing serious problems in the treatment of microbial infections. The discovery and development of new drugs is urgently needed to overcome this problem which has greatly undermined the clinical ...
Gutiérrez-Barranquero, José A., O'Gara, Fergal, Parages, María L., Reen, F. Jerry   +3 more
core   +2 more sources

Synthesis of umbelliferone derivatives in Escherichia coli and their biological activities

Journal of Biological Engineering, 2017
Background Umbelliferone, also known as 7-hydroxycoumarin, is a phenolic metabolite found in many familiar plants. Its derivatives have been shown to have various pharmacological and chemo-preventive effects on human health.
Luan Luong Chu, Ramesh Prasad Pandey, Haet Nim Lim, Hye Jin Jung, Nguyen Huy Thuan, Tae-Su Kim, Jae Kyung Sohng   +6 more
doaj   +1 more source

Recombinant expression and functional characterisation of regiospecific flavonoid glucosyltransferases from Hieracium pilosella L. [PDF]

, 2009
Five glucosyltransferases were cloned by RT-PCR amplification using total RNA from Hieracium pilosella L. (Asteraceae) inflorescences as template. Expression was accomplished in Escherichia coli, and three of the HIS-tagged enzymes, UGT90A7, UGT95A1, and
Martens, S., Matern, U., Moco, S.I.A., Vervoort, J.J.M., Witte, S.   +4 more
core   +2 more sources

Allelochemical effects on net nitrate uptake and plasma membrane H+-ATPase activity in maize seedlings

Biologia Plantarum, 2010
Seven-day-old maize seedlings grown in a nitrogen-free hydroponic culture were exposed for 48 h to 0, 100 and 300 μM trans-cinnamic, p-coumaric, ferulic, caffeic acids, umbelliferone and 200 μM KNO3.
M. R. Abenavoli, A. Lupini, S. Oliva, A. Sorgonà   +3 more
doaj   +1 more source

Investigation of the Chemical Composition, Antihyperglycemic and Antilipidemic Effects of Bassia eriophora and Its Derived Constituent, Umbelliferone on High-Fat Diet and Streptozotocin-Induced Diabetic Rats

Molecules, 2022
This study was designed to investigate the chemical profile, antihyperglycemic and antilipidemic effect of total methanolic extract (TME) of Bassia eriophora and isolated pure compound umbelliferone (UFN) in high-fat diet (HFD)- and streptozotocin (STZ)-
Abdulaziz K. Al Mouslem, Hany Ezzat Khalil, Promise Madu Emeka, Ghallab Alotaibi   +3 more
doaj   +1 more source

Data on efficacy of umbelliferone on glycoconjugates and immunological marker in 7,12-dimethylbenz(a)anthracene induced oral carcinogenesis

Data in Brief, 2017
Umbelliferone, a phenolic coumarin and dietary agent is believed to play a key role in pharmacological activities including anti-cancer and anti-oxidants effect in various in vitro and in vivo models. In present data on the pre-treatment of umbelliferone
Annamalai Vijayalakshmi, Ganapathy Sindhu   +1 more
doaj   +1 more source