Results 81 to 90 of about 384 (243)
Advanced Science, EarlyView.A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu +17 more
wiley +1 more source
An isolated umbilical point of a Willmore surface
Osaka Journal of Mathematics, 2004 This paper proves that the index of an isolated umbilic point on a Willmore surface does not exceed 1/2. The author first gives a simple explanation of why we know that there do indeed exist umbilic points on Willmore surfaces with index equal to 1/2 and hence the estimate is sharp.
openaire +4 more sources
Catastrophe optics theory unveils the localised wave aberration features that generate ghost images. [PDF]
Ophthalmic Physiol Opt, 2022 Barbero S +4 more
europepmc +1 more source
Advanced Science, EarlyView.Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Stable umbilical points of a W-congruence
22 pages, 2 ...
Craizer, Marcos, Garcia, Ronaldo Alves
openaire +2 more sources
On the Moser normal form at a non-umbilic point
Mathematische Annalen, 1978 Any analytic real hypersurface \(M^{2n+1}\) in \(\mathbb{C}^{n+1}\), \(n\geq 1\)with non-degenerate Levi form at a point \(p\) has a normal form relative to certain holomorphic coordinate systems centered at \(p\) [\textit{S. S. Chern} and \textit{J. K. Moser}, Acta math. 133 (1974), 219-271 (1975; Zbl 0302.32015)].
openaire +2 more sources
Spacelike capillary surfaces in the Lorentz-Minkowski space
, 2011 For a compact spacelike constant mean curvature surface with nonempty boundary in the three-dimensional Lorentz-Minkowski space, we introduce a rotation index of the lines of curvature at the boundary umbilic point, which was developed by Choe \cite{Choe}
JUNCHEOL PYO +3 more
core +1 more source
Umbilicity of spacelike submanifolds of Minkowski space [PDF]
, 2002 We study some properties of spacelike submanifolds in Minkowski nspace all whose points are umbilic with respect to some normal field. As a consequence of these and some results contained in [l] we obtain that being v-umbilic with respect to a parallel ...
Fuster, M. C. Romero +2 more
core +1 more source
Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
Advanced Science, EarlyView.This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon +20 more
wiley +1 more source