Results 161 to 170 of about 60,645 (326)
Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants
The FEBS Journal, EarlyView.Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan +19 more
wiley +1 more source
Az UML eszközeinek bemutatása a NetCafé rendszer tervezésén keresztül
, 2008 A dolgozat az UML eszközeinek gyakorlati alkalmazását mutatja ...
Kovács, Balázs
core
Aspect-Oriented Modeling for Representing and Integrating Security Aspects in UML Models [PDF]
, 2013 Srivas Venkatesh
openalex
Adipocyte‐specific NIK depletion enhances energy metabolism and glucose tolerance in mice
The FEBS Journal, EarlyView.Obesity is associated with reduced energy expenditure and increased hepatic lipid accumulation. This study reveals that loss of NIK in adipocytes stimulates FGF21‐driven expression of thermogenic genes, including UCP1, and mitochondrial uncoupled respiration.
Atakan Ozcan +8 more
wiley +1 more source
A Pattern Based Approach to Defining the Dynamic Infrastructure of UML 2.0
The 2U Consortium has recently submitted a proposal for the definition of the UML 2.0 infrastructure. This uses an innovative technique of rapidly “stamping out” the definition using a small number of patterns commonly found in software architecture. The
Willans, James S. +6 more
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Qualitative Requirements Elicitation of Student Requirements for Tool-supported Teaching of UML Diagrams [PDF]
, 2023 Florian Huber +3 more
openalex +1 more source
Metroeconomica, EarlyView.ABSTRACT We propose a demand‐led heterogeneous firm macroeconomic model to study the impact of an exchange rate devaluation on output and financial stability. We simulate the model and find that, in the presence of foreign debt, a devaluation can have contractionary effects.
Lucca Gustafson Rodrigues +2 more
wiley +1 more source
A Design for Origami Simulation System Using UML
, 2006 P(論文)This paper describes a design process for Origami (paper folding art) Simulation System based on UML (Unified Modeling Language). UML is one of Object-Oriented development methodologies and helps us specify, visualize, and document models of ...
石川, 洋, 44626
core
Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 6, Page 1222-1236, June 2026.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source