Results 161 to 170 of about 187,911 (271)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, Volume 16, Issue 5, Page 921-931, May 2026.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

On simulation reuse in healthcare applications. [PDF]

Simulation
Zschaler S, Mustafee N, Harper A, Monks T, Onggo BS, Currie CSM, Polack F.   +6 more
europepmc   +1 more source

Integrating Computational Thinking Into Immersive Construction Education: A Framework for VR‐Based Learning

Computer Applications in Engineering Education, Volume 34, Issue 3, May 2026.
ABSTRACT The rise of automation and robotics in construction demands educational shifts to develop core cognitive skills like computational thinking (CT). However, current learning environments often lack hands‐on, iterative problem‐solving opportunities due to safety, cost, and logistical constraints.
Rahat Hussain, Sharjeel Anjum, Yewande Abraham, Karen Rambo‐Hernandez, Abiola Akanmu, Chukwuma Nnaji   +5 more
wiley   +1 more source

SurgeryMate app: developing and evaluating a training app for surgical instruments and operating room equipment. [PDF]

BMC Med Educ
Rezayi S, Zare Z, Ashrafi AS, Shahmoradi L, Meigooni FSM.   +4 more
europepmc   +1 more source

A Systematic Review to Summarize and Critically Appraise Existing Phenotype Libraries Using Electronic Health Records

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose Pharmacoepidemiology and population health studies using electronic health care records (EHRs) must define study variables through available electronic data. These variables are operationalized through phenotypes, which are a defined set of criteria used to identify specific traits or medical conditions.
Sima Mohammadi, Cori Campbell, Miriam C. J. M. Sturkenboom, Tiago A. Vaz   +3 more
wiley   +1 more source

New geochemical and Sr-Nd-Hf isotopic constraints on the genesis of kimberlites and ultramafic lamprophyres from the Adelaide Fold Belt and Gawler Craton, South Australia. [PDF]

Mineral Petrol
Dalton H, Giuliani A, Fitzpayne A, Peters BJ.   +3 more
europepmc   +1 more source

A Bibliometric Review of the INCOSE's Model‐Based Systems Engineering Roadmap

Systems Engineering, Volume 29, Issue 3, Page 567-588, May 2026.
ABSTRACT Over the past decade, model‐based systems engineering (MBSE) has gained attention as an approach for managing system complexity, offering a shift from a document‐based to a model‐based approach. The International Council on Systems Engineering (INCOSE) sparked increasing interest when it introduced MBSE and its roadmap as part of its systems ...
Marjolein Antoinette Jannyne Velthuizen, Erwin Hofman, Marcus Vinicius Pereira Pessôa   +2 more
wiley   +1 more source

MOCRA: A multi-algorithm clinical decision support system for the early detection of ovarian cancer. [PDF]

J Ovarian Res
Safaie A, Ghaffari P, Ghaderzadeh M, Salehnasab C.   +3 more
europepmc   +1 more source

Spatial and Temporal Variability of Eastern Pacific Radiocarbon and Carbon Chemistry From the Ice Age to Today

Paleoceanography and Paleoclimatology, Volume 41, Issue 5, May 2026.
Abstract Proxy records of seawater radiocarbon (14C/C) provide strong constraints on how changes in ocean ventilation contributed to the increase in atmospheric CO2 during the termination of the last ice age (≈18,000‐to‐12,000 years ago). One outstanding problem, however, is the existence of anomalously low deglacial benthic foraminiferal 14C/C in the ...
Patrick A. Rafter, Mathis P. Hain, Elsa Arellano‐Torres, Kaustubh Thirumalai, Eric J. Tappa, Maria L. Machain‐Castillo, Martin Soto‐Jimenez, Tim DeVries, Ingrid L. Hendy, Juan C. Herguera, William R. Gray, Ryan A. Green, Frank Pavia, James W. B. Rae, John R. Southon   +14 more
wiley   +1 more source

Identification of subtypes and construction of a predictive model for novel subtypes in severe community-acquired pneumonia based on clinical metagenomics: a multicenter, retrospective cohort study. [PDF]

Front Cell Infect Microbiol
Chen S, Jiang Y, Lv D, Zheng Y, Zhang R, Dai H, Wang Z, Li S, Qi R, Xu H, Yu Y, Xu C, Lu X, Xu Y, Jin S, Wu X.   +15 more
europepmc   +1 more source