Results 81 to 90 of about 14,762,295 (297)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The International Drinking Water Supply and Sanitation Decade : review of regional and global data (as at 31 December 1983

, 1986
30 p.An evaluation of the first three years of the International Drinking Water Supply and Sanitation Decade based on the results of a survey of service levels existing in 92 developing countries at the end of 1983.
International Drinking Water Supply and Sanitation Decade
core  

Ocean Decade Vision 2030 White Papers – Challenge 2: Protect and Restore Ecosystems and Biodiversity.

This draft White Paper has been prepared as part of the Vision 2030 process being undertaken in the framework of the UN Decade of Ocean Science for Sustainable Development.
Rogers, A.d., Appeltans, W., San Diego-mcglone, M.l., Baron Aguilar, C., Mtwana Nordlund, L., Pelletier, Dominique, Darnaude, A., Stiasny, M., Martone, R., Evaux L., M., Leinen, M., Seeyave, S., Pante, E., Bograd, S.j., Allcock, L., Sequeira, A., Hwai, A. T. S., Friedman, K., Pelletier, D., Dupuis, B., San Diego-Mcglone M., L., Costello, M.j., Vavia, A., Muller-karger, F.e., Hwai, A.t.s., Rogers A., D., Soares, J., Darnaude, Audrey, Jungbluth, S., Ndah, A.b., Ndah A., B., Bograd S., J., Blanco, A., Mahapatra, P., Taylor, S., Goodwin, K., Levin, L., Costello M., J., Relano, V., Tan A. S., H., Pearlman, J., Costello, M. J.,, Evaux, L.m., Pendleton, L., Evaux, L. M., Buttigieg, P., Darnaude, A., M.   +46 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The Capability Approach and the WHO healthy ageing framework (for the UN Decade of Healthy Ageing). [PDF]

Age Ageing, 2023
Venkatapuram S, Amuthavalli Thiyagarajan J.   +1 more
europepmc   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

UN Global Action Programme and Education for Sustainable Development: A Critical Appraisal of the Evidence Base

Discourse and Communication for Sustainable Education, 2015
The United Nations (UN) proclaimed the years 2005 to 2014 the World Decade on Education for Sustainable Development (ESD). As a follow up on the World Decade, the UN launched a Global Action Programme (GAP) that is designed to set the framework for ...
Fischer Daniel, Aubrecht Elisabeth Lena, Brück Maria, Ditges Laura, Gathen Lea, Jahns Maximilian, Petersmann Moritz, Rau Jörn, Wellmann Christiane   +8 more
doaj   +1 more source

How can science help to implement the UN Decade on Ecosystem Restoration 2021-2030? [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Gnacadja L, Vidal A.
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source