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European Papers, 2018 (Series Information) European Papers - A Journal on Law and Integration, 2018 3(3), 1493-1502 | European Forum Insight of 5 November 2018 | (Table of Contents) I. Introduction. - II.
Salvo Nicolosi
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Comparative Immigration Policies for Unaccompanied Minors: A Shared Challenge
, 2023 Unaccompanied minors from the Northern-Triangle and Mexico have been arriving at the United States border in large numbers over the past decade as a result of forced migration movements.
Ramirez, Diana
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International Journal of Adolescence and YouthFor unaccompanied minors seeking asylum in Europe, the formal care they are offered can be rigid and bureaucratic, lacking the flexibility necessary to adapt the care to their needs. Researchers have documented how some caregivers do ‘extra,’ self-funded
Maha Naami +2 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Quebec's Unaccompanied Minors Programmes
Refuge, 1983 I was very much interested in the article which appeared in your publication of April '83, (Vol.2, No. 4) "Quebec's Unaccompanied Minors Programs", by Mr. John Forrester.
Madeleine LeBlanc +2 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The Right to Education for Unaccompanied Minors
, 2016 In response to the increase of unaccompanied minors seeking refuge in the United States in 2014, officials within federal, state, and local institutions readied themselves to receive and serve a greater number of child migrants in detention facilities ...
Acosta, Jeanette M.
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Institutionalization of Suffering: Vulnerability by Unaccompanied Minors [PDF]
, 2020 This dissertation focuses on the way immigration legal, social service, and charitable institutions use narratives of trauma, suffering and vulnerability to determine who is worthy of economic, social, and emotional resources. My research employs a mixed
Barahona-Lopez, Katherine Valery
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