Results 261 to 270 of about 103,359 (288)

Auditory P300 in patients with bipolar disorder and their unaffected relatives

Bipolar Disorders, 2008
Objectives:  There is evidence that genetic susceptibility may be shared between bipolar disorder (BD) and schizophrenia, but electrophysiological phenotypes which have been extensively used in studies of genetic susceptibility for schizophrenia remain far less explored in bipolar illness.
Schulze, K K, Hall, M H, McDonald, C, Marshall, N, Walshe, M, Murray, R M, Bramon, E   +6 more
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Decreased serotonin transporter binding in unaffected relatives of manic depressive patients

Biological Psychiatry, 1999
There are numerous reports of decreased binding to platelet serotonin transporter (5-HTT) in depression, suggesting that it might be considered a trait marker of depression. To further investigate whether reduced 5-HTT function could be an endophenotype in manic depressive illness, we looked for abnormalities of platelet 5-HTT among subjects who are ...
M, Leboyer, P, Quintin, P, Manivet, O, Varoquaux, J F, Allilaire, J M, Launay   +5 more
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Cortical–basal ganglia imbalance in schizophrenia patients and unaffected first-degree relatives

Schizophrenia Research, 2012
Structural brain changes are amongst the most robust biological alterations in schizophrenia, and their investigation in unaffected relatives is important for an assessment of the contribution of genetic factors. In this cross-sectional morphometry study we investigated whether volume changes in SZ are linked with genetic vulnerability and whether ...
V, Oertel-Knöchel, C, Knöchel, S, Matura, A, Rotarska-Jagiela, J, Magerkurth, D, Prvulovic, C, Haenschel, H, Hampel, D E J, Linden   +8 more
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Striatal dysfunction in patients with schizophrenia and their unaffected first-degree relatives

Schizophrenia Research, 2018
Despite empirical findings showing that patients with schizophrenia and their unaffected first-degree relatives have deficits in processing monetary incentives, it is unclear whether similar deficits could be demonstrated for affective incentives. Twenty-six patients with schizophrenia and 26 age and gender matched healthy controls; 23 unaffected first-
Zhi Li, Chao Yan, Qin-yu Lv, Zheng-hui Yi, Jian-ye Zhang, Jin-hong Wang, Simon S.Y. Lui, Yi-feng Xu, Eric F.C. Cheung, Raquel E. Gur, Ruben C. Gur, Raymond C.K. Chan   +11 more
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Pituitary volume in unaffected relatives of patients with schizophrenia and bipolar disorder

Psychoneuroendocrinology, 2008
Hypothalamic-pituitary-adrenal (HPA) axis hyperactivity has been demonstrated in both schizophrenia and bipolar disorder, but the mechanisms underlying this abnormality are still unclear. Enlarged pituitary volume has been recently reported in patients with first episode psychosis and been interpreted as a consequence of an increased activation of the ...
Mondelli, Valeria, Dazzan, Paola, Gabilondo, Andrea, Tournikioti, Kalliopi, Walshe, Muriel, Marshall, Nicolette, Schulze, Katja K., Murray, Robin M., McDonald, Colm, Pariante, Carmine M.   +9 more
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Mismatch Negativity in Schizophrenia, Unaffected First-degree Relatives, and Healthy Controls

Journal of Psychiatric Research
Mismatch negativity (MMN) amplitude is attenuated in schizophrenia patients (SZ). However, variability in illness course among SZ samples and types of deviant stimuli used in MMN paradigms have contributed to inconsistent findings across studies. Though MMN is suggested to be impaired in schizotypy, the potential link between the two is yet to be ...
Anushree Bose, Sri Mahavir Agarwal, Hema Nawani, Venkataram Shivakumar, Vanteemar S. Sreeraj, Janardhanan C. Narayanaswamy, Devvarta Kumar, Ganesan Venkatasubramanian   +7 more
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Brain volumes in familial and non‐familial schizophrenic probands and their unaffected relatives

American Journal of Medical Genetics, 2002
AbstractStructural brain abnormalities are consistently reported in schizophrenic subjects but the etiology of these abnormalities remains unclear. We tested the contribution of genetic predisposition and obstetric complications to the structural brain abnormalities found in schizophrenic probands and their relatives.
Sham, P, Schulze, K, Walshe, M, Sharma, T, Grech, A, McDonald, C, Toulopoulou, T, Chapple, B, Sigmundsson, T, Chitnis, X, Murray, RM   +10 more
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Frontal alpha asymmetry in OCD patients and unaffected first-degree relatives.

Journal of Abnormal Psychology, 2017
Frontal electroencephalographic alpha asymmetry as an indicator of trait approach and trait inhibition systems has previously been studied in individuals with obsessive-compulsive disorder (OCD) with mixed results. We explored frontal alpha asymmetry as a possible risk factor in OCD by investigating a large sample of OCD patients (n = 113), healthy ...
Rosa Grützmann, Anja Riesel, Julia Klawohn, Stephan Heinzel, Christian Kaufmann, Katharina Bey, Leonard Lennertz, Michael Wagner, Norbert Kathmann   +8 more
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Striatal volumes in affected and unaffected relatives of bipolar patients – high-risk study

Journal of Psychiatric Research, 2009
Striatal volume changes reported in bipolar disorders could represent artifacts of medication or comorbid conditions, or illness related changes, either biological predispositions or consequences of illness burden. We conducted volumetric high-risk study to investigate whether striatal volume changes represent primary biological risk factor for bipolar
Tomas, Hajek, Eva, Gunde, Claire, Slaney, Lukas, Propper, Glenda, MacQueen, Anne, Duffy, Martin, Alda   +6 more
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White Matter Density in Patients with Schizophrenia, Bipolar Disorder and Their Unaffected Relatives

Biological Psychiatry, 2005
This study sought to assess white matter density in patients and relatives with histories of bipolar disorder and/or schizophrenia.Subjects included those with schizophrenia from families affected by schizophrenia alone, those with bipolar disorder from families affected by bipolar disorder alone and those with bipolar disorder from families affected ...
Andrew M, McIntosh, Dominic E, Job, T William J, Moorhead, Lesley K, Harrison, Stephen M, Lawrie, Eve C, Johnstone   +5 more
openaire   +2 more sources