Results 61 to 70 of about 50,402 (304)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Dual clearance squeeze film damper [PDF]

open access: yes, 1985
A dual clearance hydrodynamic liquid squeeze film damper for a gas turbine engine is described. Under normal operating conditions, the device functions as a conventional squeeze film damper, using only one of its oil films.
Fleming, D. P.
core   +1 more source

Effective velocity distribution in an atom gravimeter: effect of the convolution with the response of the detection

open access: yes, 2014
We present here a detailed study of the influence of the transverse motion of the atoms in a free-fall gravimeter. By implementing Raman selection in the horizontal directions at the beginning of the atoms free fall, we characterize the effective ...
Cheng, Bing   +5 more
core   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

An Improved Centralized Control Structure for Compensation of Voltage Distortions in Inverter-Based Microgrids

open access: yesEnergies, 2018
Recently, increased use of non-linear loads has intensified the harmonic distortion and voltage unbalance in distribution systems. Inverter Based Distributed Generators (IBDGs) can be employed as distributed compensators to improve the power quality, as ...
Morteza Afrasiabi, Esmaeel Rokrok
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Evaluation of overhead lines current unbalance in meshed grids and its reduction

open access: yesJournal of Modern Power Systems and Clean Energy, 2018
This paper describes new methodology in the current unbalance calculations in meshed grids. The meshed grids, mainly the transmission ones, consist of more parts connected together which are formed using different conductor types, phase sequence ...
Jakub EHRENBERGER, Jan ŠVEC
doaj   +1 more source

Guidelines for Weighting Factors Adjustment in Finite State Model Predictive Control of Power Converters and Drives [PDF]

open access: yes, 2009
INTERNATIONAL CONFERENCE ON INDUSTRIAL TECHNOLOGY () (.2009.VICTORIA, AUSTRALIA)Model Predictive Control with a finite control set has emerged as a promising control tool for power converters and drives.
Cortés, Patricio   +7 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

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