Results 31 to 40 of about 1,121,600 (292)
Using the scaled boundary finite element method to model 2D time-dependent geotechnical engineering problems [PDF]
, 2005 The scaled boundary finite element method caters well for soil-structure interaction problems, but the formulation does not cater for the presence of changing pore pressures with time, body loads and tractions. A detailed formulation is presented in this
Hassanen, M., El-Hamalawi, A.
core +4 more sources
International Journal of Naval Architecture and Ocean Engineering, 2015 For Super-Cavitating Underwater Vehicles (SCUV), the numerical analyses and experiments in a large cavitation tunnel are carried out at relatively large Reynolds numbers.
Jung-Kyu Choi +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Numerical Simulation of Ground Effect on Circulation Control Airfoil
International Journal of Aerospace Engineering, 2022 Circulation control (CC) is used extensively to control the attitude of rudderless aircraft experiencing ground effect in take-off and landing phases. The investigation of ground effect on airfoil CC is necessary to improve flight performance and quality
Quanbing Sun +4 more
doaj +1 more source
Fourth-order operators with unbounded coefficients
Communications on Pure and Applied AnalysisWe prove that operators of the form $A=-a(x)^2Δ^{2}$, with $|D a(x)|\leq c a(x)^\frac{1}{2}$, generate analytic semigroups in $L^p(\mathbb{R}^N)$ for ...
Gregorio F., Spina C., Tacelli C.
openaire +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Scattering resonances in unbounded transmission problems with sign-changing coefficient [PDF]
, 2022 It is well-known that classical optical cavities can exhibit localized phenomena associated to scattering resonances, leading to numerical instabilities in approximating the solution.
Carvalho, Camille +3 more
core +2 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
An Approximate Solution for a Class of Ill-Posed Nonhomogeneous Cauchy Problems
Journal of Mathematics, 2021 In this paper, we consider a nonhomogeneous differential operator equation of first order u′t+Aut=ft. The coefficient operator A is linear unbounded and self-adjoint in a Hilbert space. We assume that the operator does not have a fixed sign. We associate
Nihed Teniou, Salah Djezzar
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source