Results 101 to 110 of about 64,214 (233)

Shape Derivatives of the Eigenvalues of the De Rham Complex for Lipschitz Deformations and Variable Coefficients: Part I

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT We study eigenvalue problems for the de Rham complex on varying three‐dimensional domains. Our analysis includes the Helmholtz equation as well as the Maxwell system with mixed boundary conditions and non‐constant coefficients. We provide Hadamard‐type formulas for the shape derivatives under weak regularity assumptions on the domain and its ...
Pier Domenico Lamberti   +2 more
wiley   +1 more source

Numerical Investigation of a Diffusive SIR Model: Focus on Positivity Preservation

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this paper, we consider a system of semilinear partial differential equations (PDEs) representing a spatially extended SIR epidemic model. A brief analytical investigation of the well‐posedness and positivity of the solutions is provided in the appendix, while the main focus is on the numerical treatment of the model.
Rahele Mosleh   +2 more
wiley   +1 more source

Leveraging Public Transit for Robotic Deliveries: A Column Generation Approach

open access: yesNaval Research Logistics (NRL), EarlyView.
ABSTRACT Autonomous mobile robots (AMRs) are small, electric, wheeled vehicles that operate at pedestrian speeds. In the last‐mile delivery service considered in this study, a fleet of AMRs is deployed across multiple recharging depots within a service area, from which they depart to perform point‐to‐point deliveries. We consider an operational setting
Yishay Shapira, Mor Kaspi
wiley   +1 more source

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren   +7 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Recursive Feasibility of Nonlinear Stochastic Model Predictive Control With Gaussian Process Dynamics

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT Data‐based learning of system dynamics allows model‐based control approaches to be applied to systems with partially unknown dynamics. Gaussian process regression is a preferred approach that outputs not only the learned system model but also the variance of the model, which can be seen as a measure of uncertainty.
Daniel Landgraf   +2 more
wiley   +1 more source

Adaptive Sliding Mode Control Design for Interval Type‐2 T–S Fuzzy Systems With Time Delay: An Event‐Triggered Approach

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT In this work, a new event‐triggered adaptive first‐order sliding mode control method is proposed for nonlinear systems with constant time delays, modeled by interval type‐2 Takagi–Sugeno (T–S) fuzzy systems. To handle matched disturbances with unknown upper bounds, a non‐overestimating adaptation strategy for the control coefficient is ...
Rodrigo Possidonio Noronha   +1 more
wiley   +1 more source

Safe Stabilization Using Non‐Smooth Control Lyapunov Barrier Function

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT This paper addresses the challenge of safe stabilization, ensuring the system state reaches the origin while avoiding unsafe state regions. Existing approaches that rely on smooth Lyapunov barrier functions often fail to guarantee a feasible controller. To overcome this limitation, we introduce the non‐smooth control Lyapunov barrier function (
Jianglin Lan   +3 more
wiley   +1 more source

On an Aggregation Theory for Indicators Expressing Behaviors of Complex Systems With an Application to Sustainability

open access: yesSustainable Development, EarlyView.
ABSTRACT Certain attributes of large‐scale complex systems are often expressed through sets of indicators. For example, the sustainability of an entity, be it a nation, a city, an energy system, a corporation etc., can be effectively represented by indicators and corresponding data series.
Vassilis S. Kouikoglou   +1 more
wiley   +1 more source

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