Results 121 to 130 of about 64,214 (233)

Immune escape mechanisms revealed by multifunctional nanoprobes targeting PD‐L1 in hepatic cancer progression

open access: yesVIEW, EarlyView.
The ICGB@Apt nanoprobes are designed to specifically recognize immune checkpoint molecules such as PD‐L1, thereby enabling precise monitoring of the progression from liver cirrhosis to HC. By binding to PD‐L1 on tumor cells, ICGB@Apt visualizes immune escape events and tumor metastasis while simultaneously reflecting the dynamic interaction between ...
Yiteng Meng   +5 more
wiley   +1 more source

Deciphering the cellular tumor microenvironment landscape in salivary gland carcinomas using multiplexed imaging mass cytometry. [PDF]

open access: yesJ Exp Clin Cancer Res
Mayer M   +10 more
europepmc   +1 more source

Both forest cover and land management practices explain variation in recovering pine marten densities

open access: yesWildlife Biology, EarlyView.
Robust monitoring of wildlife populations to guide interventions is fundamental to conservation and wildlife management. Understanding how landscape characteristics are influencing predator population dynamics is often vital to inform recovery strategies, management, and policy. The pine marten Martes martes is recovering in the UK; however, population
Keziah J. Hobson   +6 more
wiley   +1 more source

FROM NY‐LON TO SILK? Shifting Centres of Attention in the World's Urban Fabric

open access: yesInternational Journal of Urban and Regional Research, EarlyView.
Abstract This Interventions essay explores Silk Road urbanism's emergence as a rival to New York and London (NY‐LON) for global centre stage in Anglophone urban and regional studies. Through China's Belt and Road Initiative, more attention is being given to urban formations and associated new centralities beyond North Atlantic global/world cities ...
Tim Bunnell, Han Cheng, Wenn Er Tan
wiley   +1 more source

The dynamics of criminal collaboration: Multiplex ties in mafia networks

open access: yesCriminology, EarlyView.
Abstract This study examines how social embeddedness and multiplex relationships shape criminal collaboration within organized crime networks. Drawing on data from three major investigations into the ‘Ndrangheta, we analyze how kinship, clan affiliation, leadership, and prior interactions influence participation in meetings and phone calls.
Francesco Calderoni   +2 more
wiley   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

open access: yesAllergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery   +25 more
wiley   +1 more source

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