Results 51 to 60 of about 5,071 (202)

MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman, An‐Ping Ye, Ya‐Xian Zhang, Ming‐Yu Chen, Fang Huang, Rong Liu, Ying‐Yan Fang, Xiaochuan Wang   +7 more
wiley   +1 more source

Ensemble Docking of FDA‐Approved and Peruvian Phytochemicals Against Monkeypox Virus Telomere‐Binding Protein

ChemistrySelect, Volume 11, Issue 9, 5 March 2026.
ABSTRACT Monkeypox is a reemerging zoonotic disease that has been spreading worldwide. Different approaches are being conducted to find effective treatments for this disease. To accelerate therapeutic discovery, we propose telomere‐binding protein (TBP) as a potential drug target because of its important role during virus maturation.
Edinson Gervacio‐Villarreal, Georcki Ropón‐Palacios, Claudina Sancho, Jhon Pérez‐Silva, Kewin Otazu, Gustavo E. Olivos‐Ramirez, Karolyn Vega‐Chozo, Yaritza L. Ramirez‐Díaz, Manuel E. Chenet‐Zuta, Ivonne Navarro del Aguila, Mario De la Cruz Flores, Cinthia Aguiar, Ihosvany Camps   +12 more
wiley   +1 more source

Effect of Hewei Anshen Decoction on depressive insomnia and brain neurotransmitter levels

Sleep Research, Volume 3, Issue 1, Page 4-10, March 2026.
Abstract Objective To evaluate the therapeutic effect of Hewei Anshen Decoction (HAD) on both depressive symptoms and sleep quality in patients with depressive insomnia, and to investigate its impact on brain neurotransmitter levels. Methods Seventy‐two patients with depressive insomnia were randomly assigned to a treatment group and a control group ...
Feifei Lv, Xin Zhang, Liang Wang, Shaodan Li, Fagen Li   +4 more
wiley   +1 more source

Effect of Soil Moisture Content on Growth, Crude Drug "Cho-to-ko" Yield and Oxindole Alkaloid Content of Uncaria rhynchophylla (B. LIVING SCIENCE) [PDF]

, 1992
Uncaria rhynchophylla was cultivated by using soil with various moisture contents (20,40,60,80 or 100% of the maximum moisture content retained by soil). Both growth and crude drug "Cho-to-ko" (dried stem with hooks of U.
ミズカミ, ハジメ, コバヤシ, シゲキ, カワゾエ, サダヒロ, 小林, 茂樹, 川添, 禎浩, Ohashi, Hiromu, Kawazoe, Sadahiro, 10198, Kobayashi, Shigeki, 水上, 元, 10242, 10197, 大橋, 裕, 10199, Mizukami, Hajime, オオハシ, ヒロム   +15 more
core  

Phytochemical diversity of naturally regenerated plants in a biodiversity enrichment experiment

Journal of Ecology, Volume 114, Issue 3, March 2026.
Tree islands established within an industrial oil palm plantation promoted the recovery of phytochemical diversity through natural regeneration. Ten years after planting, untargeted metabolomics of 76 regenerating woody species detected 27,122 phytochemical features, including many novel compounds. Larger islands supported higher woody species richness
Vannesa Montoya‐Sánchez, Emmanuel Defossez, Gustavo B. Paterno, Nathaly Guerrero‐Ramírez, Gaetan Glausere, Dirk Hölscher, Holger Kreft, Bambang Irawan, Delphine Clara Zemp   +8 more
wiley   +1 more source

Uncaria tomentosa stimulates the proliferation of myeloid progenitor cells [PDF]

, 2011
Ethnopharmacological relevanceThe Asháninkas, indigenous people of Peru, use cat's claw (Uncaria tomentosa) to restore health. Uncaria tomentosa has antioxidant activity and works as an agent to repair DNA damage.
do Carmo Araújo, Maria, Farias, Iria, Júlia Farias, Dalmora, Sergio Luiz, Asbahr, Ana Carolina Cavazzin, Schetinger, Maria Rosa Chitolina, Marcio Alvarez-Silva, Maria do Carmo Araújo, Sergio Luiz Dalmora, Aloisio Luiz Benedetti, Bertol, Gustavo, Iria Farias, Alvarez-Silva, Marcio, Gustavo Bertol, Benedetti, Aloisio Luiz, Ana Carolina Cavazzin Asbahr, Zimmermann, Estevan Sonego, Maria Rosa Chitolina Schetinger, Farias, Júlia, Estevan Sonego Zimmermann   +19 more
core   +1 more source

PENGARUH GAMBIR (Uncaria gambir Roxb.) SEBAGAI ANTI HIPERKOLESTEROLEMIA

, 2022
Tanaman gambir merupakan komoditas spesifik lokasi dan unggulan daerah provinsi Sumatera Barat (Dhalimi, 2006). Gambir adalah sejenis getah yang dikeringkan yang berasal dari ekstrak remasan daun dan ranting tumbuhan bernama sama (Uncaria gambir Roxb ...
Putri, Afifah
core   +1 more source

Yokukansan, a kampo medicine, protects PC12 cells from glutamate-induced death by augmenting gene expression of cystine/glutamate antiporter system Xc-.

PLoS ONE, 2014
Effects of the kampo medicine yokukansan on gene expression of the cystine/glutamate antiporter system Xc-, which protects against glutamate-induced cytotoxicity, were examined in Pheochromocytoma cells (PC12 cells).
Hitomi Kanno, Zenji Kawakami, Kazushige Mizoguchi, Yasushi Ikarashi, Yoshio Kase   +4 more
doaj   +1 more source

A Flavonoid‐Rich Extract of Scoparia dulcis L. Exhibits Antiviral Activity against Herpes Virus Type 1

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT This study investigated the phytochemical profile, cytotoxicity, and anti‐herpetic activity of the hydroethanolic extract from Scoparia dulcis L. aerial parts. Mass spectrometry revealed the presence of 15 compounds. The extract showed low cytotoxicity in Vero cells, maintaining over 80% viability at concentrations up to 250 µg/mL.
Francisco Leandro Medeiros de Lucena Jales, Emerson Michell da Silva Siqueira, Renato Dantas‐Medeiros, Edilane Rodrigues Dantas de Araújo, Jovelina Samara Ferreira Alves, Hugo Alexandre de Oliveira Rocha, Norberto Peporine Lopes, Leandro de Santis Ferreira, Emanuella de Aragão Tavares, Silvana Maria Zucolotto   +9 more
wiley   +1 more source

Anatomia do lenho de Uncaria guianensis e U. tomentosa (Rubiaceae) do estado do Acre, Brasil Wood anatomy of Uncaria guianensis e U. tomentosa (Rubiaceae) from the State of Acre, Brazil

Acta Amazonica, 2006
As plantas de Uncaria guianensis e U. tomentosa são lianas trepadeiras, arbustos trepadores ou rasteiros ascendentes que ocorrem em amplas áreas da Amazônia brasileira e países da América Central e do Sul.
Percy A. Zevallos Pollito, Mario Tomazello   +1 more
doaj   +1 more source