Results 61 to 70 of about 5,071 (202)

Pharmacological Mechanisms of Phytochemicals and Pharmaceutical Agents in Protecting Against Methotrexate‐Induced Liver Injury

Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
Methotrexate (MTX) is a widely used chemotherapeutic and immunosuppressive agent for treating various malignancies, autoimmune diseases (AIDs), and inflammatory disorders. Despite its therapeutic efficacy, long term or high‐dose MTX treatment is associated with a significant risk of hepatotoxicity, leading to MTX‐induced liver injury (MTX‐LI).
Bushra Zia, Mouza Hasan Alqaishi Alshehhi, Azimullah Sheikh, Samir Mirza, Sandeep B. Subramanya, Shreesh K. Ojha, Priya Gusain   +6 more
wiley   +1 more source

Potential Effectiveness of Yokukansan and Lemborexant as Alternative Candidates to Benzodiazepines to Prevent Benzodiazepine Withdrawal Delirium in the Cancer Perioperative Period: A Case Report and Literature Review

Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
The combination of yokukansan and lemborexant may be an effective replacement for benzodiazepines in terms of 5‐HT, GABA, and sleep cycle. ABSTRACT Background Benzodiazepine withdrawal delirium is a serious problem, and several candidates have been proposed to manage benzodiazepine withdrawal, such as valproic acid and carbamazepine, up to now. However,
Junji Yamaguchi, Ryoichi Sadahiro, Saho Wada, Eri Nishikawa, Tatsuto Terada, Rika Nakahara, Hiromichi Matsuoka   +6 more
wiley   +1 more source

Uña de gato (Uncaria tomentosa) [PDF]

, 2000
El presente boletín genera conocimientos básicos sobre la especie Uncaria tomentosa (uña de gato), sobre sus características ecológicas, descripción de la planta, fenología, técnicas de recolección de semillas, manejo y almacenamiento de semillas, vivero
Flores Bendezú, Ymber
core   +1 more source

Multispecies Solidarity: How People and Cinchona Survived the COVID‐19 Pandemic in Loja, Ecuador

Culture, Agriculture, Food and Environment, Volume 47, Issue 2, December 2025.
ABSTRACT This article uses the case of Cinchona officinalis entrepreneurship during the COVID‐19 pandemic to explore how dynamics of care and extraction figure within the construct of multispecies solidarity. C. officinalis is an endangered medicinal tree that holds global historical significance as a natural source of quinine.
Katharine McNamara
wiley   +1 more source

Effectiveness and Safety of Perampanel in Refractory Focal Epilepsy: Real‐World Evidence From a Chinese Cohort

Brain and Behavior, Volume 15, Issue 11, November 2025.
This retrospective real‐world study of 190 Chinese patients with refractory focal epilepsy demonstrated that adjunctive PER achieved sustained responder rates (∼66%) and seizure freedom (∼27%) over 12 months, with an acceptable safety profile. Male gender, higher doses, and late add‐on predicted better outcomes, while adults experienced fewer adverse ...
Tong Yi, Luwen Huang, Wei Peng, Ting Zhang, Dong Zhou, Xiaohui Lai, Jinmei Li   +6 more
wiley   +1 more source

Cancer Prevention and Therapy With Nutritional Science: Addressing the Gap in Medical Education and Practice

MedComm, Volume 6, Issue 11, November 2025.
A plant‐based diet reduces the risk of cancer by providing essential nutrients and phytochemicals that contain anticancer properties. Osteopathic medicine's holistic approach emphasizes the interconnectedness of body systems and lifestyle factors, including nutrition, to promote overall health and prevent disease.
Taylor E. Collignon, Anupam Bishayee
wiley   +1 more source

Inventarisasi Spesies Dari Genus Uncaria Berbasis Spesimen Herbarium Universitas Andalas (ANDA) [PDF]

Penelitian mengenai jenis-jenis Uncaria telah pernah dilakukan. penelitian yang dilakukan oleh Zetra (1994) menyatakan terdapat 16 jenis Uncaria yang ditemukan di Sumatra Barat.
Wiranda, Jefri
core   +1 more source

Biologically active compounds from the genus Uncaria (Rubiaceae)

, 2014
The species of Uncaria have significant history of traditional medicinal use, for the treatment of many illnesses such as wounds, ulcers, fevers, head-aches, gastrointestinal illness, microbial infections, hypertension, and nervous disorders [6].
Koyyalamudi, Sundar R. (R11027), Sundar Rao Koyyalamudi, Reddy, Narsimha (R8453), Anjaneya Swamy Ravipati, Ravipati, Anjaneya S. (S28876), Narsimha Reddy   +5 more
core   +1 more source

DataSheet_1_Comparative and phylogenetic analysis of the complete chloroplast genomes of Uncaria (Rubiaceae) species.pdf

, 2023
The genus Uncaria is famous for its high medicinal value. However, the high morphological similarities and unclear interspecific genetic relationships have posed challenges to the classification and identification of Uncaria species.
Xingyuan Xu (12620454), Jiangpeng Dai (17693544), Shuang Zhu (3930080), Xiaoxia Gao (2302237), Zhijie Tan (17693547), Yuexia Lin (7164743), Qiaozhen Liu (15999643)   +6 more
core   +1 more source

A Near Telomere‐To‐Telomere Genome Assembly of Coffea arabica (Mundo Novo) Provides Insights Into Its Secondary Metabolism

Molecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT Arabica coffee (Coffea arabica) dominates global coffee production, accounting for over 60% of the world's coffee trade. The Mundo Novo cultivar, predominantly grown in Yunnan, China, represents a significant germplasm resource. However, the absence of a high‐quality reference genome has hindered comprehensive genetic research and in‐depth ...
Yi Liu, Hang Zong, Yaowu Xing, Xi Jiao, Zhuoya Liu, Yusheng Niu, Zhiling Yang, Shimeng Liu, Yongqiang Wang, Haodong Zhao, Xianqing Chen, Zhenzhu Li, Xiao Wang, Jing Cai, Wen Wang, Zhongkai Wang   +15 more
wiley   +1 more source