Results 61 to 70 of about 2,076,153 (275)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Improvement of Uncertainty Relations for Mixed States
, 2004 We study a possible improvement of uncertainty relations. The Heisenberg uncertainty relation employs commutator of a pair of conjugate observables to set the limit of quantum measurement of the observables. The Schroedinger uncertainty relation improves
Park, Yong Moon
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
On Uncertainty Measures of the Interval-Valued Hesitant Fuzzy Set
Advances in Fuzzy Systems, 2023 Interval-valued hesitant fuzzy sets (IVHFS), as a kind of decision information presenting tool which is more complicated and more scientific and more elastic, have an important practical value in multiattribute decision-making.
Yingjun Xu
doaj +1 more source
Entropic uncertainty measure for fluctuations in two-level electron-phonon models
, 2004 Two-level electron-phonon systems with reflection symmetry linearly coupled to one or two phonon modes (exciton and E$\otimes(b_1+b_2)$ Jahn-Teller model) exhibit strong enhancement of quantum fluctuations of the phonon coordinates and momenta due to the
Majernik, V. +2 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
AN ASSESSMENT METHOD FOR THE CONTROL SYSTEMS QUALITY
Автоматизация технологических и бизнес-процессов. Possibilities and methods of applying the concept of uncertainty in order to assess the quality of control are investigated. An analysis of the approaches currently used for uncertainty assessment is carried out.
Г. І. Манко
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source