Results 21 to 30 of about 35,778 (326)

Serum Angiopoietin-1 and -2 and VEGF are associated with severe disease in vivax malaria

Journal of Vector Borne Diseases, 2020
Background & objectives: Malaria continues to be a significant public health problem in tropical countries including India; however, there are limited tools to predict occurrence of severe disease due to malaria.
Srinivas H Gowda, Hiren Anghan, Hridesh Mishra, Kunzang Chosdol, Manasvini Bhatt, Vinod Kumar, Piyush Ranjan, Praveen Aggarwal, Naveet Wig, Manish Soneja   +9 more
doaj   +1 more source

Health Worker Factors Associated with Prescribing of Artemisinin Combination Therapy for Uncomplicated Malaria in Rural Tanzania. [PDF]

, 2013
Improving malaria case management is partially dependent on health worker compliance with clinical guidelines. This study assessed health worker factors associated with correct anti-malarial prescribing practices at two sites in rural Tanzania.
Abdulla, Salim, Amuri, Mbaraka, de Savigny, Don, Kajungu, Dan, Khatib, Rashid A, Masanja, Irene M, Njozi, Mustafa, Selemani, Majige   +7 more
core   +4 more sources

Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixed-species malaria in Gabon [PDF]

, 2012
Background: The recommendation of artemisinin combination therapy (ACT) as first-line treatment for uncomplicated falciparum malaria is supported by a plethora of high quality clinical trials.
Adegnika, Ayola A., Basra, Arti, Bélard, Sabine, Capan, Mesküre, Diop, Daisy A., Joanny, Fanny, Kleine, Christian, Kremsner, Peter G., Kurth, Florian, Mombo-Ngoma, Ghyslain, Mordmüller, Benjamin, Ramharter, Michael, Würbel, Heike   +12 more
core   +1 more source

Impact of the method of G6PD deficiency assessment on genetic association studies of malaria susceptibility. [PDF]

PLoS ONE, 2009
BACKGROUND:Clinical association studies have yielded varied results regarding the impact of glucose-6-phosphate dehydrogenase (G6PD) deficiency upon susceptibility to malaria.
Marla K Johnson, Tamara D Clark, Denise Njama-Meya, Philip J Rosenthal, Sunil Parikh   +4 more
doaj   +1 more source

Review of pyronaridine anti-malarial properties and product characteristics. [PDF]

, 2012
Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J, Borghini-Fuhrer, Isabelle, Craft, J Carl, Croft, Simon L, Duparc, Stephan, Fleckenstein, Lawrence, Rim, Han-Jong, Shin, Chang-Sik   +7 more
core   +2 more sources

Exploration of in Vivo Efficacy of Artemether-Lumefantrine Against Uncomplicated Plasmodium Falciparum Malaria in Under Fives in Tabora Region, Tanzania. [PDF]

, 2013
Tanzania adopted artemether-lumefantrine (AL) as first-line drug for uncomplicated malaria in 2006. Recently, there was an anecdotal report on high malaria recurrence rate following AL treatment in in the (urban and peri-urban), western part of Tanzania.
Hulser, Ruth, Joseph, Deokary, Kabanywanyi, Abdunoor M, Minzi, Omary Ms, Mugittu, Kefas, Premji, Zulfiqarali   +5 more
core   +3 more sources

Mouse Models of Uncomplicated and Fatal Malaria [PDF]

BIO-PROTOCOL, 2015
Mouse models have demonstrated utility in delineating the mechanisms underlying many aspects of malaria immunology and physiology. The most common mouse models of malaria employ the rodent-specific parasite species Plasmodium berghei, P. yoelii, and P.
Huang, Brian W, Pearman, Emily, Kim, Charles C   +2 more
openaire   +5 more sources

Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria [PDF]

, 2008
Besides existing artemisinin-based combination therapies, alternative safe, effective and affordable drug combinations against falciparum malaria are needed. Methylene blue (MB) was the first synthetic antimalarial drug ever used, and recent studies have
Coulibaly, Boubacar, Klose, Christina, Kouyaté, Bocar, Mansmann, Ulrich, Meissner, Peter E., Mockenhaupt, Frank P., Müller, Olaf, Schirmer, R. Heiner, Sié, Ali, Walter-Sack, Ingeborg, Zoungrana, Augustin   +10 more
core   +1 more source

Characterisation of populations at risk of sub-optimal dosing of artemisinin-based combination therapy in Africa.

PLOS Global Public Health, 2023
Selection of resistant malaria strains occurs when parasites are exposed to inadequate antimalarial drug concentrations. The proportion of uncomplicated falciparum malaria patients at risk of being sub-optimally dosed with the current World Health ...
Abena Takyi, Verena I Carrara, Prabin Dahal, Marianna Przybylska, Eli Harriss, Genevieve Insaidoo, Karen I Barnes, Philippe J Guerin, Kasia Stepniewska   +8 more
doaj   +1 more source

In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. [PDF]

, 2004
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 2003
Stepniewska, K, Taylor, W R J, Mayxay, M, Price, R, Smithuis, F, Guthmann, J P, Barnes, K, Myint, H Y, Adjuik, M, Olliaro, P, Pukrittayakamee, S, Looareesuwan, S, Hien, T T, Farrar, J, Nosten, F, Day, N P J, White, N J   +16 more
core   +2 more sources