Results 41 to 50 of about 19,796 (310)

Thiamin deficiency and uncomplicated falciparum malaria in Laos [PDF]

Tropical Medicine & International Health, 2007
SummaryObjective  Thiamin deficiency complicates severe Plasmodium falciparum malaria in Thailand and may contribute to acidosis. We therefore estimated the frequency of biochemical thiamin deficiency in patients presenting with uncomplicated falciparum malaria in southern Laos.Methods  Red cell transketolase activation coefficients (α) were measured ...
Mayxay, M, Taylor, A, Khanthavong, M, Keola, S, Pongvongsa, T, Phompida, S, Phetsouvanh, R, White, N, Newton, P   +8 more
openaire   +2 more sources

Protective efficacy of malaria case management and intermittent preventive treatment for preventing malaria mortality in children: a systematic review for the Lives Saved Tool

BMC Public Health, 2011
Background The Lives Saved Tool (LiST) model was developed to estimate the impact of the scale-up of child survival interventions on child mortality. New advances in antimalarials have improved their efficacy of treating uncomplicated and severe malaria.
Steketee Richard W, Eisele Thomas P, Thwing Julie   +2 more
doaj   +1 more source

Effectiveness of peer‐supervision on pediatric fever illness treatment among registered private drug sellers in East‐Central Uganda: An interrupted time series analysis

Health Science Reports, 2021
Rationale, aims, and objectives Appropriate treatment of pediatric fever in rural areas remains a challenge and maybe partly due to inadequate supervision of licensed drug sellers.
Arthur Bagonza, Freddy Eric Kitutu, Stefan Peterson, Andreas Mårtensson, Milton Mutto, Phyllis Awor, David Mukanga, Henry Wamani   +7 more
doaj   +1 more source

Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia. [PDF]

, 2011
BACKGROUND: Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients.
Njie, Fanta, Bisseye, C, Nwakanma, D, Snell, P., Walton, Robert T., Conway D., Nwakanma, Davis, Cyrille Bisseye, Joof F., Sesay, Sanie, Milligan P., Walton, R, Sanie Sesay, Snell Paul, Joof, F., Snell P., Cheung, Yin Bun, Milligan Paul, Sesay S., Sesay, S, Bisseye C., Diatta Mathurin, Bisseye, Cyrille, Njie, F, Dunyo, Samuel, Janha, R., Adiamoh, M, Adiamoh, Majidah, Njie F., Janha, Ramatoulie, Temple B., Temple, B., Diatta, Mathurin, Cheung Yin Bun, Ramatoulie Janha, Yin Bun Cheung, Nwakanma, D., Diatta M., David Conway, Temple, Beth, Snell, P, Walton R., Janha, R, Sisay Joof Fatou, Robert Walton, Sisay Joof, F, Samuel Dunyo, Conway, D., Sirugo, G, Sirugo, G., Dunyo, S., Nwakanma D., Temple, B, Sirugo, Giorgio, Janha Ramatoulie, Dunyo S., Njie, F., Dunyo, S, Nwakanma Davis, Paul Milligan, Walton Robert, Beth Temple, Conway, David, Mathurin Diatta, Paul Snell, Bisseye Cyrille, Sesay, S., Cheung, YB, Temple Beth, Janha R., Adiamoh, M., Milligan, Paul, Milligan, P., Cheung Y.B., Bisseye, C., Fatou Sisay Joof, Walton, Robert, Sesay Sanie, Diatta, M., Conway David, Sirugo G., Diatta, M, Majidah Adiamoh, Davis Nwakanma, Njie Fanta, Adiamoh M., Snell, Paul, Milligan, P, Sisay Joof, Fatou, Sirugo Giorgio, Dunyo Samuel, Conway, D, Fanta Njie, Adiamoh Majidah, Giorgio Sirugo, Cheung, Y. B.   +95 more
core   +1 more source

Oral quinine for the treatment of uncomplicated malaria

BMJ, 2009
Is ineffective in outpatients and should be used only in rare cases Artemisinin combination therapy is the first line treatment for uncomplicated malaria in nearly all malaria endemic countries in sub-Saharan Africa. This treatment is relatively expensive, but it kills parasites faster than any other method and has few adverse effects.1 The ...
Reyburn, Hugh, Mtove, George, Hendriksen, Ilse, von Seidlein, Lorenz   +3 more
openaire   +1 more source

Increased Risk for Severe Malaria in HIV-1–infected Adults, Zambia

Emerging Infectious Diseases, 2009
To determine whether HIV-1 infection and HIV-1–related immunosuppression were risk factors for severe malaria in adults with some immunity to malaria, we conducted a case–control study in Luanshya, Zambia, during December 2005–March 2007.
Victor Chalwe, Doreen Mukwamataba, Joris Menten, John Kamalamba, Modest Mulenga, Umberto D’Alessandro, Jean-Pierre Van Geertruyden   +6 more
doaj   +1 more source

Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi [PDF]

, 2009
Sulphadoxine-pyrimethamine (SP) is the only single dose therapy for uncomplicated malaria, but there is widespread resistance. At the time of this study, artemether-lumefantrine (AL) and chlorproguanil-dapsone (CPD), both multi-dose regimes, were ...
Hughes Dyfrig A, Mavuto Mukaka, Montgomery, Jacqui, Peter A Winstanley, Wootton, Dan, Winstanley Peter A, David G Lalloo, Molyneux Malcolm E, Bell, David J., Ward, Steve, Ward, Steve A., Chimpeni Phillips, Mukaka, Mavuto, Dyfrig A Hughes, Hughes, Dyfrig A., Steve A Ward, Wootton, Daniel G., Molyneux, Malcolm E., Lalloo David G, Phillips Chimpeni, Malcolm E Molyneux, Bell David J, Kayange Noel, Jacqui Montgomery, Ward Steve A, David J Bell, Noel Kayange, Mukaka Mavuto, Hughes, Dyfrig, Kayange, Noel, Lalloo, David G., Wootton Dan, Lalloo, David; id_orcid, Chimpeni, Phillips, Winstanley, Peter, Montgomery Jacqui, Dan Wootton, Winstanley, Peter A.   +37 more
core   +1 more source

Ketotifen in treatment of uncomplicated falciparum malaria

Saudi Medical Journal, 2000
The present in vivo study evaluates the potential use of ketotifen, a tricyclic antihistaminic drug, in treatment of Sudanese patients with uncomplicated Plasmodium falciparum malaria (19-38 years).Four groups of patients (each has 15) were randomly selected and treated by chloroquine (25mg/kg wt) in comparison with regimen combinations of ketotifen (0.
A M, Ibrahim, E R, Elhag, S E, Mustafa
openaire   +2 more sources

Artemether-lumefantrine for treating uncomplicated falciparum malaria [PDF]

Cochrane Database of Systematic Reviews, 2003
Artemether-lumefantrine is being promoted by the World Health Organization for treating uncomplicated malaria. It is expensive. We sought evidence of its superiority over existing treatment regimens.To compare artemether-lumefantrine with other antimalarial drugs for treating uncomplicated falciparum malaria.We searched the Cochrane Infectious Diseases
A A, Omari, C, Preston, P, Garner
openaire   +3 more sources

Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study. [PDF]

, 2012
BACKGROUND: Artemisinin-based combination therapy (ACT) has been promoted as a means to reduce malaria transmission due to their ability to kill both asexual blood stages of malaria parasites, which sustain infections over long periods and the immature ...
Mwita, A., Elling, B.F., MacArthur, John R, Mwita, Alex, Mills, Anne, Tanner, M., Goodman, C. A., Roberts, J.M., Skarbinski, J., Elling, B. F., Elling, Berty F, Kahigwa, E., Roberts, J. M., Lyimo, T., Khatib, R.A., Njau, J. D., Somi, Masha F, Kahigwa, Elizeus, Njau, J.D., Macarthur, J. R., Somi, M.F., Kachur, S Patrick, Roberts, Jacquelin M, Skarbinski, Jacek, Goodman, Catherine A, Kabanywanyi, Abdunoor M, Smith, Ernest E, Goodman, C.A., Genton, B., Abdulla, S. M., Bloland, Peter B, Gutman, J. R., Kabanywanyi, A.M., Gutman, J.R., Lyimo, Thomas, Kachur, S.P., Bloland, P.B., Njau, Joseph D, Bloland, P. B., Mshinda, Hassan, Genton, Blaise, Tanner, Marcel, MacArthur, J.R., Somi, M. F., Abdulla, Salim M, Smith, E. E., Smith, E.E., Kachur, S. P., Kabanywanyi, A. M., Khatib, R. A., Mshinda, H., Gutman, Julie R, Abdulla, S.M., Mills, A., Khatib, Rashid A   +54 more
core   +1 more source