Results 21 to 30 of about 19,796 (310)

Artemisinin derivatives for treating uncomplicated malaria [PDF]

Cochrane Database of Systematic Reviews, 1999
Artemisinin derivatives are a relatively new group of drugs with antimalarial properties. As resistance to other antimalarial drugs continues to increase, artemisinin drugs may be useful alternatives.The objective of this review was to assess the effects of artemisinin drugs for treating uncomplicated falciparum malaria.We searched the Cochrane ...
H M, McIntosh, P, Olliaro
openaire   +2 more sources

A randomised controlled trial to assess the efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Peru [PDF]

, 2007
Background. Multi-drug resistant falciparum malaria is an important health problem in the Peruvian Amazon region. We carried out a randomised open label clinical trial comparing mefloquine-artesunate, the current first line treatment in this region, with
Casapia, M, Bernasconi, Andrea, Torres, Kathy, Grande, Tanilu, Erhart, Annette, Llanos-Cuentas, A., Umberto D'Alessandro, D'Alessandro Umberto, Caterina Fanello, Torres, K., Christopher Delgado, Grande, T., Casapia Martin, Casapia, M., D'Alessandro, U., Delgado, C, Fanello, C., Grande, T, Llanos-Cuentas Alejandro, Gamboa Dioni, Delgado Christopher, Erhart, A., Bernasconi, A., Tanilu Grande, Torres Kathy, Martin Casapia, Delgado, Christopher, Erhart, A, Fanello Caterina, Torres, K, Llanos-Cuentas, A, Andrea Bernasconi, Llanos-Cuentas, Alejandro, Delgado, C., Gamboa, Dioni, Bernasconi Andrea, Gamboa, D, Fanello, C, Fanello, Caterina, Gamboa, D., Bernasconi, A, Kathy Torres, Casapia, Martin, Alejandro Llanos-Cuentas, D'Alessandro, Umberto, Dioni Gamboa, Annette Erhart, D'Alessandro, U, Grande Tanilu, Erhart Annette   +49 more
core   +1 more source

Chlorproguanil-dapsone for treating uncomplicated malaria [PDF]

Cochrane Database of Systematic Reviews, 2004
In Africa, malaria is often resistant to chloroquine and sulfadoxine-pyrimethamine. Chlorproguanil-dapsone is a potential alternative.To compare chlorproguanil-dapsone with other antimalarial drugs for treating uncomplicated falciparum malaria.We searched the Cochrane Infectious Diseases Group Specialized Register (May 2004), CENTRAL (The Cochrane ...
Bukirwa H, Garner P, Critchley J
openaire   +3 more sources

Characterisation of populations at risk of sub-optimal dosing of artemisinin-based combination therapy in Africa.

PLOS Global Public Health, 2023
Selection of resistant malaria strains occurs when parasites are exposed to inadequate antimalarial drug concentrations. The proportion of uncomplicated falciparum malaria patients at risk of being sub-optimally dosed with the current World Health ...
Abena Takyi, Verena I Carrara, Prabin Dahal, Marianna Przybylska, Eli Harriss, Genevieve Insaidoo, Karen I Barnes, Philippe J Guerin, Kasia Stepniewska   +8 more
doaj   +1 more source

Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria in the setting of three different chemopreventive regimens. [PDF]

, 2015
BACKGROUND: The burden of malaria remains high for children in parts of Africa despite the use of insecticide-treated bed nets (ITNs). Chemoprevention has the potential of reducing the malaria burden; however, limited data exist on the efficacy and ...
Tamara Clark, Grant Dorsey, Achan, Jane, Dorsey, Grant, Mwangwa, Florence, Kapisi, James, Kamya, Moses, Seyi Soremekun, Moses Kamya, Bigira, Victor, Soremekun, Seyi, Florence Mwangwa, Clark, Tamara, Kinara, Stephen, James Kapisi, Victor Bigira, Stephen Kinara, Jane Achan   +17 more
core   +1 more source

STATUS HEMATOLOGI PENDERITA MALARIA SEREBRAL

Majalah Kedokteran Andalas, 2009
AbstrakMalaria masih merupakan masalah kesehatan masyarakat dunia. Berdasarkan klasifikasi klinis, malaria dibedakan atas malaria berat dan malaria tanpa komplikasi.
Nurhayati Nurhayati
doaj   +1 more source

Open-label comparative clinical study of chlorproguanil−dapsone fixed dose combination (Lapdap™) alone or with three different doses of artesunate for uncomplicated plasmodium falciparum malaria [PDF]

, 2008
The objective of this study was to determine the appropriate dose of artesunate for use in a fixed dose combination therapy with chlorproguanil−dapsone (CPG−DDS) for the treatment of uncomplicated falciparum ...
Peter A Winstanley, Nyirenda, Maggie, Kanjala, Maxwell K., Molyneux, Malcolm, Sam Dunyo, Stephan Duparc, Paula L Kirby, Winstanley Peter A., Kirby, Paula L., Blencowe, Hannah, Daniel G Wootton, Woessner, Mary, Thomas Kanyok, Stephen Ward, Opara, Hyginus, Molyneux Malcolm, Winstanley, Peter A, Wootton Daniel G., Maggie Nyirenda, Ward, Stephen, Dunyo, Sam, Giancarlo A Biagini, Kanjala, Maxwell K, Nyirenda Maggie, Kanyok Thomas, Maxwell K Kanjala, Opara Hyginus, Duparc, Stephan, Kanyok, Thomas, Queen Dube-Mbeye, Duparc Stephan, Malcolm Molyneux, Neate, Colin, Biagini, Giancarlo A, Biagini Giancarlo A., Ward Stephen, Kirby Paula L., Wootton, Daniel G., Wootton, Daniel G, Kirby, Paula L, Hannah Blencowe, Mary Woessner, Kanjala Maxwell K., Molyneux, Malcolm E., Biagini, Giancarlo A., Woessner Mary, Dube-Mbeye Queen, Colin Neate, Hyginus Opara, Neate Colin, Blencowe Hannah, Dunyo Sam, Winstanley, Peter, Dube-Mbeye, Queen   +53 more
core   +1 more source

CLINICAL ASPECTS OF UNCOMPLICATED AND SEVERE MALARIA

Mediterranean Journal of Hematology and Infectious Diseases, 2012
The first symptoms of malaria, common to all the different malaria species, are nonspecific and mimic a flu-like syndrome. Although fever represents the cardinal feature, clinical findings in malaria are extremely diverse and may range in severity from mild headache to serious complications leading to death, particularly in falciparum malaria.
BARTOLONI, ALESSANDRO, ZAMMARCHI, LORENZO   +1 more
openaire   +5 more sources

Exploration of in Vivo Efficacy of Artemether-Lumefantrine Against Uncomplicated Plasmodium Falciparum Malaria in Under Fives in Tabora Region, Tanzania. [PDF]

, 2013
Tanzania adopted artemether-lumefantrine (AL) as first-line drug for uncomplicated malaria in 2006. Recently, there was an anecdotal report on high malaria recurrence rate following AL treatment in in the (urban and peri-urban), western part of Tanzania.
Minzi, O.M.S., Abdunoor M Kabanywanyi, Kabanywanyi, A.M., Mugittu, K., Joseph, Deokary, Premji, Zulfiqarali, Mugittu, Kefas, Deokary Joseph, Omary MS Minzi, Kabanywanyi, Abdunoor M, Kefas Mugittu, Ruth Hulser, Zulfiqarali Premji, Joseph, D., Premji, Zul, Hulser, Ruth, Minzi, Omary Ms, Hulser, R.   +17 more
core   +1 more source

Oxidative Stress and Hemoglobin Level of Complicated and Uncomplicated Malaria Cases among Children: A Cross-Sectional Study in Kumasi Metropolis, Ghana

Journal of Tropical Medicine, 2019
Introduction. Malaria is a leading cause of mortality among children below 5 years in Ghana. Its parasites are known to cause the degradation of hemoglobin, resulting in the production of reactive oxygen species and hence oxidant stress.
Kwabena Nsiah, Bernard Bahaah, Bright Oppong Afranie, Simon Koffie, Emmanuel Akowuah, Sampson Donkor   +5 more
doaj   +1 more source