Results 61 to 70 of about 19,796 (310)

Plasmodium falciparum population dynamics during the early phase of anti-malarial drug treatment in Tanzanian children with acute uncomplicated malaria. [PDF]

, 2011
BACKGROUND\ud \ud This study aimed to explore Plasmodium falciparum population dynamics during the early phase of anti-malarial drug treatment with artemisinin-based combination therapy in children with clinical malaria in a high transmission area in ...
Carlsson, A.M, Abdulla, Salim, Christopher Membi, Veiga, I.M, Ngasala, Billy E, Gil, J Pedro, Abdulla, S., Carlsson, Anja M, Premji, Z., Björkman, Anders, Premji, Zul, Dahlström, Sabina, Veiga, I.M., Carlsson, Anja M., Anders Björkman, Abdulla Salim, Ngasala, B.E, Lars Rombo, Billy E Ngasala, Veiga, Isabel M, Gil, J. P., Björkman Anders, Zul Premji, Membi, Christopher, Mårtensson, Andreas, Ngasala, Billy E., Bjorkman, A., Martensson, A., Salim Abdulla, Isabel M Veiga, Mårtensson Andreas, Gil J, Ngasala Billy E, Gil, J.P., Rombo, L., Premji Zul, Rombo Lars, Carlsson Anja M, Andreas Mårtensson, Membi Christopher, Anja M Carlsson, Dahlstrom, S., Membi, C., Rombo, Lars,, Carlsson, A.M., Sabina Dahlström, J Gil, Dahlström Sabina, Veiga, Maria Isabel, Rombo, Lars, Veiga Isabel M, Ngasala, B.E.   +51 more
core   +1 more source

Hyponatraemia and hypokalaemia in adults with uncomplicated malaria in Thailand [PDF]

Tropical Doctor, 2008
In a retrospective study of 1415 patients aged 15 and over, we determined the incidence of clinically important hyponatraemia and hypokalaemia in adults with uncomplicated malaria. On admission, serum concentrations of sodium (135–145 mmol/L) and potassium (3.5–5.0 mmol/L) were found outside these reference ranges in 81% of patients.
Vipa, Thanachartwet, Srivicha, Krudsood, Noppadon, Tangpukdee, Weerapong, Phumratanaprapin, Udomsak, Silachamroon, Wattana, Leowattana, Polrat, Wilairatana, Gary M, Brittenham, Sornchai, Looareesuwan, Guy H, Neild   +9 more
openaire   +2 more sources

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Genetic diversity of Plasmodium falciparum isolates from patients with uncomplicated and severe malaria based on msp-1 and msp-2 genes in Gublak, North West Ethiopia

Malaria Journal, 2019
Background Malaria infection can present with a wide variety of symptoms, ranging from mild to severe. Plasmodium falciparum isolates in uncomplicated and severe malaria infections may have different parasite genetic profiles. This study was conducted to
Hussein Mohammed, Kedir Hassen, Ashenafi Assefa, Kalkidan Mekete, Gemechu Tadesse, Girum Taye, Robert J. Commons   +6 more
doaj   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial. [PDF]

, 2011
BACKGROUND: The use of artemisinin-based combination therapy (ACT) is currently recommended for treating uncomplicated malaria. The objective was to assess the efficacy and safety of repeated administrations of two fixed-dose presentations of ACT ...
Gaye Oumar, Ali Gueye, Corinne Tchania, Cissé, Badara, Tchania Corinne, Ibrahima Ndiaye, Barry Aichatou, Tine Roger, Gueye Ali, Tine, Roger, Ndiaye Daouda, Ndiaye, Ibrahima, Ndiaye, Daouda, Daouda Ndiaye, Valérie Lameyre, Gueye, Ali, Ndiaye Jean-Louis A, Roger Tine, Aichatou Barry, Tchania, Corinne, Faye, Babacar, Babacar Faye, Lameyre, Valérie, Cissé Badara, Ndiaye Ibrahima, Barry, Aichatou, Gaye, Oumar, Oumar Gaye, Faye Babacar, Ndiaye, Jean-Louis A, Jean-Louis A Ndiaye, Lameyre Valérie, Badara Cissé   +32 more
core   +1 more source

Artificial Intelligence‐Driven Network Pharmacology: A Methodological Paradigm Shift Bridging Traditional Wisdom and Modern Science

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang, Sile Hu, Rigahai Ji, Riguna A, Siqige Hao, Ma Zhuo, Yi‐Hung Chen, Bisihalatu Hu, Ulana Bai, Xigui Hada   +9 more
wiley   +1 more source

Malaria trends in districts that were targeted and not-targeted for seasonal malaria chemoprevention in children under 5 years of age in Guinea, 2014–2021

BMJ Global Health
Background Seasonal malaria chemoprevention (SMC) is a main intervention to prevent and reduce childhood malaria. Since 2015, Guinea has implemented SMC targeting children aged 3–59 months (CU5) in districts with high and seasonal malaria transmission ...
Donal Bisanzio, Richard Reithinger, Thierno Diallo, Mamadou Sitan Keita, Alioune Camara, Timothée Guilavogui, Hamidou Barry, Adam Preston, Lamine Bangoura, Eliane Mbounga, Lia S Florey, Jean-Luc Taton, Aissata Fofana   +12 more
doaj   +1 more source

Possible treatment failure of artemether-lumefantrine in an Italian traveler with uncomplicated falciparum malaria.

Mediterranean Journal of Hematology and Infectious Diseases, 2011
Artemisinin-combination therapies (ACTs) are recommended for the treatment of uncomplicated malaria in endemic areas with multidrug resistant Plasmodium falciparum.
Ernestina Carla Repetto, Claudio Giacomazzi, Antonio Traverso   +2 more
doaj   +1 more source

Trends in malaria morbidity following the introduction of artesunate plus amodiaquine combination in M'lomp village dispensary, south-western Senegal. [PDF]

, 2008
BACKGROUND: In Thailand, South Africa and Zanzibar, a decrease in malaria morbidity was observed following the introduction of artemisinin-based combination therapy (ACT).
Senghor Paul, Sophie Sarrassat, Le Hesran, Jean Yves, Paul Senghor, Hesran Jean, Le Hesran, Jean-Yves, Senghor, Paul, Jean Yves Le Hesran, Sophie SophieSarrassat, Sarrassat, Sophie, Sarrassat Sophie, Jean Hesran   +11 more
core   +1 more source