Results 41 to 50 of about 35,778 (326)

Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan. [PDF]

, 2004
To provide advice on the rational use of antimalarial drugs, Médecins Sans Frontières conducted a randomized, an open label efficacy study in Kajo Keji, an area of high transmission of malaria in southern Sudan.
Epicentre, Krishna S, Kshirsagar NA, National Malaria Administration/Unicef, Ochong EO, Omari AA, Seidlein L, UN/OCHA, Vugt M, WHO, WHO, WHO, WHO, WHO/Roll Back Malaria   +13 more
core   +2 more sources

Effectiveness of peer‐supervision on pediatric fever illness treatment among registered private drug sellers in East‐Central Uganda: An interrupted time series analysis

Health Science Reports, 2021
Rationale, aims, and objectives Appropriate treatment of pediatric fever in rural areas remains a challenge and maybe partly due to inadequate supervision of licensed drug sellers.
Arthur Bagonza, Freddy Eric Kitutu, Stefan Peterson, Andreas Mårtensson, Milton Mutto, Phyllis Awor, David Mukanga, Henry Wamani   +7 more
doaj   +1 more source

Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine:pharmacokinetic and dosage-related findings from a clinical trial in Uganda [PDF]

, 2006
BACKGROUND: A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one of the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to inadequate nutrition, and a lack ...
Babigumira, Joseph, Bajunirwe, Francis, Biraro, Samuel, Checchi, Francesco, Ferradini, Laurent, Fogg, Carole, Grandesso, Francesco, Guthmann, Jean-Paul, Kigozi, Isaac, Kiguli, James, Kyomuhendo, Juliet, Piola, Patrice, Ruzagira, Eugene, Taylor, Walter R. J.   +13 more
core   +3 more sources

CLINICAL ASPECTS OF UNCOMPLICATED AND SEVERE MALARIA

Mediterranean Journal of Hematology and Infectious Diseases, 2012
The first symptoms of malaria, common to all the different malaria species, are nonspecific and mimic a flu-like syndrome. Although fever represents the cardinal feature, clinical findings in malaria are extremely diverse and may range in severity from mild headache to serious complications leading to death, particularly in falciparum malaria.
BARTOLONI, ALESSANDRO, ZAMMARCHI, LORENZO   +1 more
openaire   +5 more sources

Protective efficacy of malaria case management and intermittent preventive treatment for preventing malaria mortality in children: a systematic review for the Lives Saved Tool

BMC Public Health, 2011
Background The Lives Saved Tool (LiST) model was developed to estimate the impact of the scale-up of child survival interventions on child mortality. New advances in antimalarials have improved their efficacy of treating uncomplicated and severe malaria.
Steketee Richard W, Eisele Thomas P, Thwing Julie   +2 more
doaj   +1 more source

Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in Zambia. [PDF]

, 2005
In the Maheba Refugee Settlement, in the clinics supported by Medecins Sans Frontieres, all children aged up to 5 years with a confirmed diagnosis of uncomplicated falciparum malaria are treated with the combination of sulfadoxine/pyrimethamine (SP) and ...
Bloland PB, Contamin H, National Malaria Control Centre, Nosten F, Peterson DS, Trape JF, Vasconcelos KF, White NJ, World Health Organisation (WHO), World Health Organisation (WHO)   +9 more
core   +2 more sources

Increased Risk for Severe Malaria in HIV-1–infected Adults, Zambia

Emerging Infectious Diseases, 2009
To determine whether HIV-1 infection and HIV-1–related immunosuppression were risk factors for severe malaria in adults with some immunity to malaria, we conducted a case–control study in Luanshya, Zambia, during December 2005–March 2007.
Victor Chalwe, Doreen Mukwamataba, Joris Menten, John Kamalamba, Modest Mulenga, Umberto D’Alessandro, Jean-Pierre Van Geertruyden   +6 more
doaj   +1 more source

Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]

, 2010
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Annerberg, Anna, Ashton, Michael, Björkman, Anders, Dahlström, Sabina, Färnert, Anna, Gil, Pedro, Hietala, Sofia Friberg, Lindegårdh, Niklas, Mårtensson, Andreas, Ngasala, Billy, Premji, Zul   +10 more
core   +4 more sources

Quinine Pharmacokinetic-Pharmacodynamic Relationships in Uncomplicated Falciparum Malaria [PDF]

Antimicrobial Agents and Chemotherapy, 2003
ABSTRACTThe relationships between the pharmacokinetic properties of quinine during a 7-day treatment course and the therapeutic response were studied in 30 adult patients with uncomplicated falciparum malaria monitored for ≥28 days. All patients received a 7-day oral quinine regimen either alone (n= 22) or in combination with rifampin (n= 8).
Pukrittayakamee, S, Wanwimolruk, S, Stepniewska, K, Jantra, A, Huyakorn, S, Looareesuwan, S, White, N   +6 more
openaire   +2 more sources

Increased use of malaria rapid diagnostic tests improves targeting of anti-malarial treatment in rural Tanzania: implications for nationwide rollout of malaria rapid diagnostic tests. [PDF]

, 2012
: BACKGROUND: The World Health Organization recommends parasitological confirmation of all malaria cases. Tanzania is implementing a phased rollout of malaria rapid diagnostic tests (RDTs) for routine use in all levels of care as one strategy to increase
Baraka Amuri, CIR Chandler, D Bell, D Payne, D Zurovac, Dan Kajungu, DS Ishengoma, HA Williams, IM Masanja, Irene M Masanja, J Faucher, Jacek Skarbinski, L Gilson, LJ Manham, Majige Selemani, Rashid Khatib, S Patrick Kachur, SA Harvey, TJ O’Dempsey, United Republic of Tanzania. Ministry of Health and Social Welfare, V D’Acremont, W Rennie, World Health Organization   +22 more
core   +2 more sources