Results 11 to 20 of about 423 (145)

Efficacy and safety of native type II collagen in modulating knee osteoarthritis symptoms: a randomised, double‐blind, placebo‐controlled trial [PDF]

Journal of Experimental Orthopaedics, 2022
Purpose Knee osteoarthritis (OA) is the most common form of clinical arthritis in middle‐aged and older individuals. Undenatured or native type II (TII) collagen derived from the chicken sternum has a good therapeutic effect on relieving severe pain of ...
Cheng Luo, Weike Su, Ying Song, Shalini Srivastava   +3 more
doaj   +3 more sources

Molecular Mechanisms of Action of Undenatured Type II Collagen: Experimental and Clinical Evidence

Современная ревматология, 2022
In the treatment of joint diseases, including osteoarthritis (OA), the use of standardized extracts of undenatured type II collagen (UDC-II) is promising. It is known that UDC-II is involved in the regulation of innate and adaptive immunity (reduction of
O. A. Gromova, I. Yu. Torshin, A. M. Lila   +2 more
doaj   +2 more sources

The potential of undenatured type II collagen against arthritis: a review

Collagen and Leather
The increasing global aging population has led to a continual rise in the prevalence of bone and joint diseases, posing challenges to both the quality of life for patients and healthcare resources. Type II collagen, a pivotal protein for sustaining joint
Yuhao Zhou, Yuer Zhang, Hongjie Dai, Yuhao Zhang, Yu Fu   +4 more
doaj   +2 more sources

On the prospects for the use of undenatured type II collagen in the treatment of osteoarthritis and other joint diseases

Современная ревматология, 2022
Standardized extracts of undenatured type II collagen (UC-II) are used as alternative approaches to the treatment of osteoarthritis (OA). The effect of UC-II extracts is associated with the modulation of the mechanisms of innate and acquired immunity, a ...
O. A. Gromova, I. Yu. Torshin, A. M. Lila, O. A. Shavlovskaya   +3 more
doaj   +2 more sources

Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis [PDF]

Scientific Reports, 2021
The current work aimed to examine the properties of oral supplementation of niacinamide and undenatured type II collagen (UCII) on the inflammation and joint pain behavior of rats with osteoarthritis (OA). Forty-nine Wistar rats were allocated into seven
Kazim Sahin, Osman Kucuk, Cemal Orhan, Mehmet Tuzcu, Ali Said Durmus, Ibrahim Hanifi Ozercan, Nurhan Sahin, Vijaya Juturu   +7 more
doaj   +4 more sources

A Comparison of Clinical Outcomes Among Undenatured Collagen Type II, Glucosamine Sulfate, and Diacerein on Osteoarthritic Knee Treatment: A Randomized Clinical Trial [PDF]

JBJS Open Access
Background:. Knee osteoarthritis (OA) causes significant disability with limited effective treatments. Undenatured collagen type II (UC-II), prescription-grade crystalline glucosamine sulfate (pCGS), and diacerein have been proposed as alternatives to ...
Rapeepat Narkbunnam, MD, Kit Awirotananon, MD, Keerati Chareancholvanich, MD, Chaiwat Achawakulthep, MD, Nath Adulkasem, MD, Swist Chatmaitri, MD, Paphon Hirunyachoke, MD, Chaturong Pornrattanamaneewong, MD   +7 more
doaj   +2 more sources

Efficacy of oral nutrition supplementation enriched with hydroxymethylbutyrate (HMB) and undenatured type-II collagen (UC-II) combined with exercise training on osteoarthritis-related outcomes among adults with knee osteoarthritis in Klang Valley of Malaysia: study protocol for a randomised controlled trial [PDF]

BMJ Open
Introduction Knee osteoarthritis (OA) is a serious public health problem since it is linked to loss of muscular function and independence, especially in older adults. In this study, the researchers have proposed a randomised controlled trial with a three-
Suzana Shahar, Yee Xing You, Sumaiyah Mat, Munirah Ismail, Anastasia Xin Wei Yap, Devinder Kaur Ajit Singh, Ching Phang Chong, Nor Hamdan Mohamad Yahaya, Juliana Fairuz Maktar, Rizal Abdul Rani, Theng Choon Ooi, Wan Chien Han, Lee Kuan Kwan, Centhyea Centhyea   +13 more
doaj   +2 more sources

Efficacy and Safety Assessment of a Dietary Supplement in a Rat Model of Osteoarthritis and Dogs with Arthritic Signs [PDF]

Animals
BYVET JOINT HEALTM (BJH) contains mucopolysaccharide protein, chondroitin sulfate, type II collagen, and omega-3 fatty acids, which protect and prevent osteoarthritis (OA)-associated tissue damage and degradation in dogs and cats.
Geon A Kim, Mi-Jin Lee, Eun Pyo Kim, Gun Ho Heo, Seung Gyu Oh, Se Chang Park, Byeong Chun Lee, Sang O Park   +7 more
doaj   +2 more sources

Oncoprotective effects of chondroprotectors: glucosamine, chondroitin sulfate and undenatured type II collagen

Фармакоэкономика, 2023
Objective: to systematize fundamental, clinical, and epidemiological data on the oncoprotective effects of chondroprotectors: chondroitin sulfate (CS), glucosamine (including glucosamine sulfate, GS), and undenatured type II collagen (UC-II).Material and
I. Yu. Torshin, A. G. Chuchalin, O. A. Gromova   +2 more
doaj   +2 more sources

Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals [PDF]

Animals, 2020
OA is quite common in companion animals, especially in large breed dogs and horses. Collagen, the most abundant protein of mammals, has specific connective tissue types for skin, bones, reticulate, basal lamina, bones, cell surfaces, while type II ...
Hasan Gencoglu, Cemal Orhan, Emre Sahin, Kazim Sahin   +3 more
doaj   +3 more sources