Results 31 to 40 of about 423 (145)

[Retracted] Healthcare and Scientific Treatment of Knee Osteoarthritis

Journal of Healthcare Engineering, Volume 2022, Issue 1, 2022., 2022
Knee osteoarthritis is a chronic degenerative disease companied with chronic knee pain and dysfunction. However, the etiology and pathogenesis of knee osteoarthritis were unclear. Currently, age, diet, trauma, obesity, and inheritance are the main risk factors. The major pathological hallmarks of knee osteoarthritis included subchondral bone sclerosis,
Huan Wang, Baoan Ma, Rahim Khan
wiley   +1 more source

UBC13 is an RNF213‐associated E2 ubiquitin‐conjugating enzyme, and Lysine 63‐linked ubiquitination by the RNF213‐UBC13 axis is responsible for angiogenic activity

FASEB BioAdvances, Volume 3, Issue 4, Page 243-258, April 2021., 2021
Abstract Moyamoya disease (MMD) is a cryptogenic vascular disorder in the intracranial arteries. RING protein 213 (RNF213) is the susceptibility gene for MMD, and encodes a RING domain and a Walker motif. Herein, we identified UBC13 (UBE2N) as an E2 ubiquitin‐conjugating enzyme for RNF213 E3 ubiquitin ligase by yeast two‐hybrid screening with a ...
Toshiyuki Habu, Kouji H. Harada
wiley   +1 more source

On the use of chondroitin sulfate, glucosamine sulfate and undenatured type II collagen for back and limb pain and osteoarthritis

Неврология, нейропсихиатрия, психосоматика, 2022
Backpain and pain in the limbs are often associate with the destruction of the cartilage and bone tissue of the joint, which affects the nerve terminals and leads to an exacerbation of pain symptoms (as happens, for example, in osteoarthritis).
O. A. Gromova, I. Y. Torshin, A. M. Lila
doaj   +1 more source

Cow's Milk Positively Impacts Bone Formation by Regulating the Osteocalcin Pathway Compared to Transgenic and Non-Transgenic Soy-Based Beverages in BALB/c Mice. [PDF]

Mol Nutr Food Res
Comparison of the effects of cow's milk and transgenic soy‐based beverages on bone health in BALB/c mice. Cow's milk promoted higher trabecular density; improved bone structure; and increased osteocalcin, calcium, and phosphorus levels. The non‐transgenic soy beverage led to reduced cortical thickness and increased diaphysis diameter, while the ...
Costa EP, Sarandy MM, Lozi AA, Martins MTS, Mattosinhos PDS, Dias MMDS, Matta SLP, Novaes RD, Gonçalves RV.   +8 more
europepmc   +2 more sources

The value of undenatured collagen for the normalization of the function of the cartilaginous tissue of the joints

Медицинский совет, 2022
Among the proteins of the human body, collagen accounts for at least 25–45% collagen; it is an essential structural component of skeletal tissues, connective tissue of internal organs (heart, intestines, lungs, liver, kidneys), as well as blood vessels ...
I. S. Dydykina, P. S. Kovalenko, A. A. Kovalenko, A. V. Aboleshina   +3 more
doaj   +1 more source

The Study of undenatured type II collagen in the knee osteoarthri [PDF]

International Journal of Orthopaedics Traumatology & Surgical Sciences, 2019
Introduction: Medical management of osteoarthritis has evovlved considerably over last two decades. The purpose of the present study was to asses the outcome of collagen type II IN osteoarthritis of knee joint. Methods: one hundred randomly selected patients who received a daily dose of UC-II (40 mg) for 120 days.
openaire   +1 more source

Pain Reduction and Tolerance of Type II Undenatured Collagen (UC-II) Collagen in Patients with Knee Osteoarthritis

, 2023
Osteoarthritis (OA) is the most common cause of pain and disability in adults. Dietary supplements such as undenatured type II collagen (UC-II) have shown to have some benefits in OA treatment. This study aimed to assess changes in pain levels among knee OA patients treated with UC-II for 6 months.
Tomás Fernando Fernández-Jaén, Carlos García de Vega, Paula Sáiz, Per Björk, Elena Rodríguez-Iñigo, Juan Manuel López-Alcorocho, Franchek Drobnic, Pedro Guillén-García   +7 more
openaire   +1 more source

Effects of Exercise Combined with Undenatured Type II Collagen on Endurance Capacity, Antioxidant Status, Muscle Lipogenic Genes and E3 Ubiquitin Ligases in Rats

Animals, 2021
The current study aimed to investigate the effect of exercise combined with undenatured type II collagen (UCII) administration on endurance capacity, lipid metabolism, inflammation, and antioxidant status in rats.
Cemal Orhan, Emre Sahin, Besir Er, Mehmet Tuzcu, Andrey P. Lopes, Nurhan Sahin, Vijaya Juturu, Kazim Sahin   +7 more
doaj   +1 more source

Efficacy of undenatured and hydrolyzed type II collagen in the treatment of pain syndrome

Russian Medical Inquiry, 2022
Collagens play an important structural role and contribute to the mechanical properties, organization and shape of tissues. In musculoskeletal system diseases (MSD), the amount of type II collagen in the cartilage extracellular matrix significantly decreases. Degradation and reduction of type II collagen are associated with osteoarthritis (OA).
O.A. Shavlovskaya, I.A. Bokova, I.D. Romanov, N.I. Shavlovsky   +3 more
openaire   +1 more source

Pharmaconutraceutical Chondroguard®TRIO – chondroprotector with immunomodulatory activity

Неврология, нейропсихиатрия, психосоматика, 2023
Understanding the major pathological pathways and the key molecules involved in the pathogenesis of inflammatory processes in joints, particularly in osteoarthritis (OA), is crucial for drug and pharmaconutraceuticals development.
O. A. Shavlovskaya, Yu. D. Yukhnovskaya, I. D. Romanov, I. A. Bokova   +3 more
doaj   +1 more source