Comparative Study of Collagen Gels Extracted from Different Sources. [PDF]
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Undenatured type II collagen and its role in improving osteoarthritis
Ageing Research Reviews, 2023Osteoarthritis (OA) is a degenerative joint disease, affecting 32.5 million US adults or 242 million people worldwide. There is no cure for OA. Many animal and clinical trials showed that oral administration of undenatured type II collagen could significantly reduce the incidence of OA or alleviate the symptoms of articular cartilage.
Mouming Zhao, Jianping Wu, Lin Zheng
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Water-Soluble Undenatured Type II Collagen Ameliorates Collagen-Induced Arthritis in Mice
Journal of Medicinal Food, 2013Earlier studies have reported the efficacy of type II collagen (C II) in treating rheumatoid arthritis (RA). However, a few studies have investigated the ability of the antigenic collagen to induce oral tolerance, which is defined as active nonresponse to an orally administered antigen.
Manashi Bagchi +2 more
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Safety and toxicological evaluation of undenatured type II collagen
Toxicology Mechanisms and Methods, 2010Previous research has shown that undenatured type II collagen is effective in the treatment of arthritis. The present study evaluated the broad-spectrum safety of UC-II by a variety of toxicological assays including acute oral, acute dermal, primary dermal irritation, and primary eye irritation toxicity.
Debasis Bagchi +2 more
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This study aimed to investigate the effects of dynamic high-pressure homogenization (DHPH), dynamic high-pressure microfluidization (DHPM), and wet media milling (WMM) processes on the particle size, microstructure, triple helix structure, wettability and suspension stability of insoluble undenatured type II collagen (IUC-II).
Jinfang Liu, Like Mao
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Points of undenatured type II collagen application in musculoskeletal pain syndromes treatment
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2022The dominant collagen of the cartilaginous matrix in adults is type II collagen. The amount of type II collagen in the intercellular matrix of cartilage is significantly reduced against the background of musculoskeletal system diseases. The basis of articular cartilage is hyaline cartilage tissue consisting of chondrocytes with tissue-specific antigens
O.A. Shavlovskaya +2 more
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