Results 111 to 120 of about 35,714 (290)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

FDI and regional economic integration in SAARC region: problems and prospects [PDF]

open access: yes
Regional integration has the potential to promote economic development in member countries irrespective of size and the level of growth. This potential can be exploited only through deeper cooperation.
Ansari, Nasim, Khan, Tamanna
core   +1 more source

Export instability and political violence in underdeveloped countries [PDF]

open access: yes, 1971
There have been few attempts to empirically delineate and assess the importance of "external" or "international" factors in the study of comparative politics and political development.
Moul, William Brian
core  

Evaluation and Obstacle Factors of Renewable Energy Substitution Potential in Underdeveloped Rural Areas of China [PDF]

open access: yes
The energy consumption structure in underdeveloped rural areas of China has long been dominated by fossil fuels. Such a structure not only makes it difficult to improve the rural living environment but also hinders the stable development of the rural ...
Sheng Zhong, Mingting Shi
core   +1 more source

TYPOLOGY AND STRUCTURE OF ECONOMIC GROWTH [PDF]

open access: yesRevista Romana de Economie, 2005
The paper proposes and applies a region classification method, within Romania’s economiccomplex, depending on the level and dynamics of regional output indicators (for instance, GDP –industrial production, labour productivity, etc.) per capita as ...
Gheorghe ZAMAN,, Zizi Goschin
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gas Market Integration: Global Trends and Implications for the EAS Region [PDF]

open access: yes
East Asia is already the main destination of the world's commercial liquefied natural gas (LNG). However, the gas markets in the EAS area are either underdeveloped or fragmented. The objectives of this study are twofold, namely, i) to present a review of
Yanrui WU
core  

City and regional planning education : response of selected North American institutions to the needs of underdeveloped countries [PDF]

open access: yes, 1971
On the assumption that the North American city and regional planning education has been of questionable value for underdeveloped countries, this study examines two major questions: a) how has this education system responded to the academic needs of ...
Rizvi, Amjad Ali Bahadur
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Conflicts and Regional Underdevelopment: A Review of Lake Chad Basin Region

open access: yes, 2022
This paper has carefully examined conflicts and regional underdevelopment, a review of the Lake Chad Basin region. This work started out by exploring Nigeria’s foreign policy and the counter-insurgency in the Chad Basin region. This paper makes it clear that Nigeria’s foreign policy has been poised to end insurgency in this region.
openaire  

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