Results 101 to 110 of about 1,449,284 (281)

Extreme sacrifice: sudden cardiac death in the US Fire Service [PDF]

, 2013
Firefighting is a hazardous profession which has claimed on average the lives of 105 US firefighters per year for the past decade. The leading cause of line-of-duty mortality is sudden cardiac death, which accounts for approximately 45% of all ...
Barr, David A, Kales, Stefanos N, Smith, Denise L   +2 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Análise da concordância da codificação de causa básica de óbito por acidentes de trânsito

Revista de Saúde Pública
OBJETIVO: Avaliar a concordância de informações pesquisadas sobre causa básica de óbito por acidente de trânsito e compará-las com as codificações feitas a partir das Declarações de Óbitos.
Roberto M. Ladeira, Mark D. C. Guimarães   +1 more
doaj  

Low rate of reporting of confirmed AIDS-related deaths using BI-1663 forms by private medical practitioners in the Mafikeng, North West Province [PDF]

, 2015
The aim of the study was to investigate the experiences and perceptions of medical practitioners about the implementation of the current death notification form (BI-1663) in cases of confirmed AIDS-related deaths. The study focused on reporting patterns
Akinnusi, David M., Molosi, L. D.
core   +1 more source

Myomata of the Uterus as an Underlying Cause of Precipitous Death [PDF]

, 1980
Arthur B. King, William C. Luft
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Comparing identification of children and young people with a life limiting condition from cause of death with use of an ICD-10 coding framework applied to routine clinical data

International Journal of Population Data Science, 2017
Objectives To compare methods of estimating prevalence of life limiting conditions (LLC) among children and young people (CYP) using (i) cause of death recorded on death certificates and (ii) diagnostic codes in routinely collected inpatient and birth ...
Stuart Jarvis, Lorna Fraser
doaj   +1 more source

Underlying cause of death at medical facilities in Xaiyabouli Province, Lao People's Democratic Republic. [PDF]

Nagoya J Med Sci, 2022
Thanavanh B, Hackpaserd S, Inthaphatha S, Kariya T, Suzuki Y, Yamamoto E, Hamajima N.   +6 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

SensRORing cholesterol to drive protumoral myelopoiesis

Molecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source