Results 101 to 110 of about 1,552,146 (293)

Mortalidade infantil em município da região Centro-Oeste Paulista, Brasil, 1990 a 1992

Revista de Saúde Pública
INTRODUÇÃO: A mortalidade infantil em Presidente Prudente, SP (Brasil), foi estudada no período de 1990 a 1992, a partir de aplicação de métodos para obtenção de diagnóstico coletivo que orientassem a identificação e escolha de estratégias de controle de
Jaime de O. Gomes, Augusto H. Santo
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

We only die once... but from how many causes? [PDF]

, 2016
Analysing causes of death provides a betterunderstanding of long-term mortality trends. InFrance, the death certificates completed by physiciansgenerally mention several causes of death (2.4 onaverage in 2011).
Barbieri, M, Demuru, E, Denissov, G, Désesquelles, A, Egidi, V, Frova, L, Gamboni, A, Goldberger, N, Grundy, E, Marshall, C, Meslé, F, Pappagallo, M, Pechholdova, M, Sakkeus, L   +13 more
core  

Androgen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles. [PDF]

, 2016
Despite aggressive treatment for localized cancer, prostate cancer (PC) remains a leading cause of cancer-related death for American men due to a subset of patients progressing to lethal and incurable metastatic castrate-resistant prostate cancer (CRPC).
Hoang, David T., Iczkowski, Kenneth A., Kilari, Deepak, Nevalainen, Marja T., See, William   +4 more
core   +2 more sources

Validade das informações ocupação e causa básica em declarações de óbito de Botucatu, São Paulo

Cadernos de Saúde Pública
O objetivo deste trabalho é estudar a validade das informações sobre ocupação habitual e causa básica em declarações de óbito (DO) de moradores de Botucatu falecidos nesta cidade.
Ricardo Cordeiro, Eduardo Rommel Olivencia Peñaloza, Chrystiano Fonseca Cardoso, Daniela Barros Cortez, Eric Kakinami, Jacques José Gomes de Souza, Maria Tereza de Moraes Souza, Ricardo Augusto Fernandes, Rodrigo Fernando Guercia, Tarso Adoni   +9 more
doaj  

National and provincial burden of interstitial lung disease mortality in China, 2013–2021: a nationwide analysis of trends and underlying cause of death

Respiratory Research
Background The national and provincial epidemiological characteristics of interstitial lung disease (ILD) mortality remain unknown in China. To assess ILD mortality trends, causes, and regional disparities in China (2013–2021).
Fanshu Yan, Lingling Yu, Zifang Zhou, Lijun Wang, Maigeng Zhou, Zhuoli Zhang, Peng Yin   +6 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Urinary Tubular Injury Biomarkers Are Associated With ESRD and Death in the REGARDS Study. [PDF]

, 2018
IntroductionUrinary neutrophil gelatinase-associated lipocalin (uNGAL) and urinary kidney injury molecule-1 (uKIM-1) are established markers of subclinical acute kidney injury.
Bennett, Michael, Cushman, Mary, Dubin, Ruth F, Judd, Suzanne, Parikh, Chirag, Peralta, Carmen A, Powe, Neil, Sarnak, Mark, Scherzer, Rebecca, Shlipak, Michael, Warnock, David G   +10 more
core  

Confiabilidade da declaração de causa básica de mortes infantis em região metropolitana do sudeste do Brasil

Revista de Saúde Pública
A partir de dados coletados para um estudo sobre a mortalidade infantil na região metropolitana de Belo Horizonte, MG, Brasil, foi selecionada uma amostra aleatória de óbitos infantis ocorridos em 1989, para avaliar a concordância da causa básica de ...
Elisabeth F. Mendonça, Eugênio M.A. Goulart, José A.D. Machado   +2 more
doaj  

ANALYSIS OF MORTALITY FROM MUSCULOSKELETAL DISEASES AS UNDERLYING AND MULTIPLE CAUSES IN THE RESIDENTS OF THE TULA REGION

Научно-практическая ревматология, 2018
Musculoskeletal diseases (MSDs) are a topical medical, social, and economic problem. According to the 2015 data, MSDs in the structure of primary morbidity were 3.9% and those in the structure of mortality were 0.2% in the Russian Federation.
D. Sh. Vaysman, V. N. Sorotskaya, E. S. Nikitina   +2 more
doaj   +1 more source