Results 141 to 150 of about 1,449,284 (281)

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

Multiple causes of death in old age [PDF]

What is known about the nature of fatal diseases and injuries is based largely upon the tradition of identifying a single condition present at death as the underlying cause. As stated on the U .S.
National Center for Health Statistics (U.S.)
core  

A Method for Identifying Underlying Causes of Death in Epidemiological Study.

, 2000
Tamiko Iwasaki, Toshio Miyake, Sumio Ohshima, Shinichi Kudo, Takesumi Yoshimura   +4 more
openalex   +2 more sources

Medication Use in Multiple Sclerosis: A Population‐Based Comparison With the General Danish Population

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen, Henrik Horwitz, Ida M. Heerfordt, Elisabeth Framke, Melinda Magyari   +4 more
wiley   +1 more source

Dynamics and structure of mortality from chronic coronary artery disease among men and women in the Russian Federation in 2014-2023

Российский кардиологический журнал
Aim. To assess the dynamics of non-standardized (NSMR) and standardized mortality rates (SMR) of chronic coronary artery disease (CAD), the contribution to all-cause mortality, as well as the dynamics and structure of chronic CAD among men and women in ...
R. N. Shepel, I. V. Samorodskaya, E. P. Kakorina, O. M. Drapkina   +3 more
doaj   +1 more source

The consistency rate of causes of Death in different components of child mortality Surveillance System in hospitals affiliated with the Shahrekord University of Medical Sciences [PDF]

, 2017
Background and aims: Child mortality Surveillance System is Iranian children mortality database nationwide and internationally. The aim of this study was to investigate one of the the most important features of data quality, i.e.
Aghdak, Pejman., Asadpour, Nabiollah., Deris, Fatemeh., Malek-Farsani, Shakiba., Saghaeiannejad Isfahani, Sakineh.   +4 more
core  

Quantitative Iron Measurements in the Basal Ganglia of NBIA Patients Using QSM: Insights From a Tertiary Center

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurodegeneration with brain iron accumulation (NBIA) comprises rare genetic disorders characterized by predominantly extrapyramidal symptoms and iron deposition in the basal ganglia. Conventional magnetic resonance imaging (MRI) detects qualitative changes but cannot accurately quantify iron accumulation. Quantitative susceptibility
Özge Uygun, Alpay Özcan, Fuat Kaan Aras, Evrim Bozdemir, Sibel Uğur İşeri, Murat Gültekin, Nihan Hande Akçakaya, Orkhan Mammadov, Gülay Kır, Dilek İnce Günal, Neşe Tuncer, Fatma Betül Özdilek, Banu Özen Barut, Ercan Köse, Hülya Apaydın, Asuman Ali, Sultan Çağırıcı, Pınar Topaloğlu, Alp Dinçer, Zuhal Yapıcı   +19 more
wiley   +1 more source

Mortality from chronic ischaemic heart disease in the Russian Federation: are there enough data for analysis and decision-making?

Кардиоваскулярная терапия и профилактика
Aim. To discuss the role of coding the underlying cause of death based on International Statistical Classification of Diseases and Related Health Problems, 10th Revision (ICD-10) in changing the standardized mortality rates (SMR) from various chronic ...
R. N. Shepel, I. V. Samorodskaya, E. P. Kakorina, O. M. Drapkina   +3 more
doaj   +1 more source

Assessment of COVID-19 as the Underlying Cause of Death Among Children and Young People Aged 0 to 19 Years in the US.

JAMA Netw Open, 2023
Flaxman S, Whittaker C, Semenova E, Rashid T, Parks RM, Blenkinsop A, Unwin HJT, Mishra S, Bhatt S, Gurdasani D, Ratmann O.   +10 more
europepmc   +1 more source

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald, Michela Guglieri, Dragana Vučinić, Gyula Acsadi, John F. Brandsema, Claudio Bruno, Erika L. Finanger, Amy Harper, Mercedes Lopez Lobato, Riccardo Masson, Nuria Muelas, Francina Munell, Yoram Nevo, Yann Péréon, Han Phan, Valeria A. Sansone, Mariacristina Scoto, Tracey Willis, Richard S. Finkel, Krista Vandenborne, Sara Cazzaniga, Silvia Montrasio, Federica Alessi, Paolo Bettica, Eugenio Mercuri, for the Givinostat Study 51 Investigators, the Cooperative International Neuromuscular Research Group (CINRG) Duchenne Natural History Study (DNHS) Investigators, the ImagingDMD Investigators, Enrico Bertini, Giacomo Pietro Comi, Eugenio Maria Mercuri, Giuseppe Vita, Sonia Messina, Claudio Bruno, Riccardo Masson, Valeria Sansone, Nathalie Goemans, Liesbeth De Waele, Laurent Servais, Teresa Gidaro, Odile Boespflug‐Tanguy, Yann Péréon, Jessika Johannsen, Astrid Blaschek, Ulrike Schara‐Schmidt, Erik Niks, Imelda de Groot, Saskia Houwen‐van Opstal, Andres Nascimento, Juan Jesus Vilchez, Nuria Muelas, Francina Munell, Marcos Madruga Garrido, Mercedes Lopez Lobato, Michaela Guglieri, Tracey Willis, Stefan Spinty, Daniel Hawcutt, Mariacristina Scoto, Jean K. Mah, Laura McAdam, Kathryn Selby, Katherine Mathews, Craig McDonald, Craig Zaidman, Barry Byrne, John Brandsema, Gyula Acsadi, Chamindra Laverty, Amy Harper, Erika Finanger, Han Phan, Yoram Nevo, Vedrana Milic Rasic, Dragana Vucinic   +74 more
wiley   +1 more source