Results 51 to 60 of about 1,489,428 (293)

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Diferenciais geográficos, socioeconômicos e demográficos da qualidade da informação da causa básica de morte dos idosos no Brasil Geographic, demographic, and socioeconomic differences in quality of data on cause of death in Brazilian elders

Cadernos de Saúde Pública, 2011
Identificaram-se diferenciais geográficos e socioeconômicos do padrão de qualidade da informação sobre a causa básica de morte dos idosos no Brasil.
Solange Kanso, Dalia Elena Romero, Iúri da Costa Leite, Edgar Nunes de Moraes   +3 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Maternal deaths and mortality due to a maternal underlying cause of death [PDF]

Ao mensurar-se mortalidade materna, é necessário distinguir ' mortes por causas maternas' e 'mortes maternas' Para a Organização Mundial da Saúde-OMS-,mortes maternas são as que ocorrem na gestação, no parto e até 42 dias após o parto; e mortes por ...
GOTLIEB, Sabina Léa Davidson, LAURENTI, Ruy, MELLO JORGE, Maria Helena Prado de   +2 more
core   +1 more source

Intérêt de l’analyse des causes multiples dans l’étude de la mortalité aux grands âges : l’exemple français [PDF]

, 2004
En France, la plus grande part des décès se produit aux âges élevés et même très élevés. Le décès est alors souvent l’aboutissement d’un processus complexe qui met en jeu plusieurs affections.
Désesquelles, Aline, Meslé, France
core   +1 more source

Using verbal autopsy to measure causes of death: the comparative performance of existing methods [PDF]

, 2014
Background: Monitoring progress with disease and injury reduction in many populations will require widespread use of verbal autopsy (VA). Multiple methods have been developed for assigning cause of death from a VA but their application is restricted by ...
Ali, S.M., Atkinson, C., Baqui, A.H., Black, R., Dandona, L., Dantzer, E., Darmstadt, G.L., Das, V., Dhingra, U., Dutta, A., Fawzi, W., Flaxman, A.D., Freeman, M.K., Gomez, S., Hernandez, B., James, S.L., Joshi, R., Kalter, H.D., Kumar, A., Kumar, V., Lopez, A. D., Lozano, R., Lucero, M., Mahende, C.J.L., Mehta, S., Ohno, S.L., Phillips, D., Premji, Zul, Ramirez-Villalobos, D., Remolador, H., Riley, I., Romero, M., Said, M., Sanvictores, D., Sazawal, S., Serina, P., Stewart, A., Tallo, V., Vahdatpour, A.   +38 more
core   +8 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Maternal Death in Indonesia: Follow-up Study of the 2010 Indonesia Population Census [PDF]

, 2016
Background: Among ASEAN countries, Indonesia is the country with high maternal mortality ratio (MMR) and unable to reach target of reduction of MMR. In order to reduce the MMR target, the government of Indonesia needs evidence to evaluate and design the ...
Afifah, T. (Tin), Pangaribuan, L. (Lamria), Rizkianti, A. (Anissa), Saptarini, I. (Ika), Senewe, F. P. (Felly), Tejayanti, T. (Teti), Usman, Y. (Yuslely)   +6 more
core   +2 more sources

Studying the Degree of Diagnostic Agreement between Medical Records and Death Certificates in Loghman Hospital in 2005

مجله اپیدمیولوژی ایران, 2007
Background & Objectives: There is little doubt about the importance of accurate statistics and reliable information in the promoting community health and optimizing health care.
A Akbarzadeh Bagheban, E Maserat, M Hemmati   +2 more
doaj