Results 51 to 60 of about 1,449,284 (281)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Diferenciais geográficos, socioeconômicos e demográficos da qualidade da informação da causa básica de morte dos idosos no Brasil Geographic, demographic, and socioeconomic differences in quality of data on cause of death in Brazilian elders

Cadernos de Saúde Pública, 2011
Identificaram-se diferenciais geográficos e socioeconômicos do padrão de qualidade da informação sobre a causa básica de morte dos idosos no Brasil.
Solange Kanso, Dalia Elena Romero, Iúri da Costa Leite, Edgar Nunes de Moraes   +3 more
doaj   +1 more source

Angka Kematian Dan Faktor Risiko Stroke Sebagai Penyebab Dasar Kematian Di Kabupaten Padang Pariaman Provinsi Sumatera Barat [PDF]

, 2016
Mortality data are one of important indicators for the publich health The aim of this study is to know about the death rate, characteristics and risk factors of stroke as underlying cause of death in Padang Pariaman district.
Bisara, D. (Dina), Ghani, L. (Lannywati), Irianto, J. (Joko), Konadi, L. (Laurentia), Pangaribuan, L. (Lamria), Senewe, F. (Felly), Sulistyowati, N. (Ning), Teja, T. (Teti)   +7 more
core   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Using verbal autopsy to measure causes of death: the comparative performance of existing methods [PDF]

, 2014
Background: Monitoring progress with disease and injury reduction in many populations will require widespread use of verbal autopsy (VA). Multiple methods have been developed for assigning cause of death from a VA but their application is restricted by ...
Ali, S.M., Atkinson, C., Baqui, A.H., Black, R., Dandona, L., Dantzer, E., Darmstadt, G.L., Das, V., Dhingra, U., Dutta, A., Fawzi, W., Flaxman, A.D., Freeman, M.K., Gomez, S., Hernandez, B., James, S.L., Joshi, R., Kalter, H.D., Kumar, A., Kumar, V., Lopez, A. D., Lozano, R., Lucero, M., Mahende, C.J.L., Mehta, S., Ohno, S.L., Phillips, D., Premji, Zul, Ramirez-Villalobos, D., Remolador, H., Riley, I., Romero, M., Said, M., Sanvictores, D., Sazawal, S., Serina, P., Stewart, A., Tallo, V., Vahdatpour, A.   +38 more
core   +8 more sources

We only die once... but from how many causes? [PDF]

, 2016
Analysing causes of death provides a betterunderstanding of long-term mortality trends. InFrance, the death certificates completed by physiciansgenerally mention several causes of death (2.4 onaverage in 2011).
Barbieri, M, Demuru, E, Denissov, G, Désesquelles, A, Egidi, V, Frova, L, Gamboni, A, Goldberger, N, Grundy, E, Marshall, C, Meslé, F, Pappagallo, M, Pechholdova, M, Sakkeus, L   +13 more
core  

Maternal Death in Indonesia: Follow-up Study of the 2010 Indonesia Population Census [PDF]

, 2016
Background: Among ASEAN countries, Indonesia is the country with high maternal mortality ratio (MMR) and unable to reach target of reduction of MMR. In order to reduce the MMR target, the government of Indonesia needs evidence to evaluate and design the ...
Afifah, T. (Tin), Pangaribuan, L. (Lamria), Rizkianti, A. (Anissa), Saptarini, I. (Ika), Senewe, F. P. (Felly), Tejayanti, T. (Teti), Usman, Y. (Yuslely)   +6 more
core   +2 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Studying the Degree of Diagnostic Agreement between Medical Records and Death Certificates in Loghman Hospital in 2005

مجله اپیدمیولوژی ایران, 2007
Background & Objectives: There is little doubt about the importance of accurate statistics and reliable information in the promoting community health and optimizing health care.
A Akbarzadeh Bagheban, E Maserat, M Hemmati   +2 more
doaj