Results 41 to 50 of about 84,473 (267)

Swallowing and Communication in Cockayne Syndrome: Clinical Characteristics and Management

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cockayne syndrome (CS) is an ultrarare genetic disorder associated with genes encoding proteins involved in DNA repair. The clinical course of CS involves neurodevelopmental and neurodegenerative features, including swallowing and communication impairments.
Abigail M. Spoden, Katlyn E. McGrattan, Peter B. Kang   +2 more
wiley   +1 more source

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source

Prevalence of and Factors Associated with Undernutrition in a Geriatric Outpatient Setting: Results from a Multidimensional Nutritional Assessment

Siriraj Medical Journal, 2018
Objective: To determine the prevalence of and factors associated with undernutrition in older patients in a geriatric outpatient setting. Methods: A cross-sectional study in people aged 65 years or older was conducted at a geriatric outpatient clinic in ...
Chalobol Chalermsri, Prasert Assantachai, Pornpoj Pramyothin, Napaporn Pengsorn, Weerasak Muangpaisan   +4 more
doaj   +3 more sources

Maternal‐to‐Infant Transfer of Medications for Type 2 Diabetes Mellitus Via Breastmilk: A Systematic Review of Available Evidence and Clinical Guidelines

Clinical Pharmacology &Therapeutics, EarlyView.
This review evaluates the available pharmacokinetic data on the plasma‐to‐breastmilk transfer of first‐ and second‐line T2DM drugs against available clinical guideline recommendations. A list of drug therapies for treating T2DM was generated from national and international clinical guidelines.
Katherine Richardson, Joshua Kiptoo, Beatrice Mpora Odongkara, Francis Williams Ojara, Catriona Waitt   +4 more
wiley   +1 more source

Building better barriers: how nutrition and undernutrition impact pediatric intestinal health

Frontiers in Immunology, 2023
Chronic undernutrition is a major cause of death for children under five, leaving survivors at risk for adverse long-term consequences. This review focuses on the role of nutrients in normal intestinal development and function, from the intestinal ...
Sarah F. Andres, Yang Zhang, Madeline Kuhn, Brian Scottoline   +3 more
doaj   +1 more source

Geo-additive models of childhood undernutrition in three sub-Saharan African countries [PDF]

, 2009
We investigate the geographical and socioeconomic determinants of childhood undernutrition in Malawi, Tanzania and Zambia, three neighbouring countries in southern Africa, using the 1992 Demographic and Health Surveys.
Besag, Caputo, Eilers, Fahrmeir, Fahrmeir, Filmer, Guilkey, Kammann, Kandala, Kandala, Klasen, Klasen, Lang, Nyovani, Smith, Spiegelhalter, Stephenson, UNICEF, World Health Organization, World Health Organization, World Health Organization   +20 more
core   +1 more source

Reduced Oligodendrocyte Density and Axonal Caliber Associated With Mitochondrial Alterations in the White Matter of Chronically‐Starved Mice

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with extreme weight loss, hyperactivity, and amenorrhea. Neuroimaging studies revealed brain atrophy and disruption of white matter integrity in the corpus callosum (CC) of patients with AN. However, the underlying pathophysiological mechanisms remain unclear.
Stephan Lang, Annelie Zimmermann, Kaja Dickert, Hanna Rupprecht, Julia Priebe, Fabienne Haberland, Hanna‐Sophia Henschke, Katharina Schuster, Marcus Frank, Linda Frintrop   +9 more
wiley   +1 more source

Undernutrition among under-five children in Western Maharashtra

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Background: Undernutrition in under-five children still remains a major public health problem. Most of the under-five deaths are due to undernutrition, putting the child at more risk of catching common infections.
Shweta Gangurde, Sudhir L Jadhav, Hetal Waghela, Kajal Srivastava   +3 more
doaj   +1 more source

Latent Trajectories of Body Mass Index and Depressive Symptoms in Inpatients With Anorexia Nervosa: Predictors and Outcomes

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Inpatient treatment aimed at weight restoration and psychiatric stabilization is often required for individuals with anorexia nervosa (AN). This study aimed to identify distinct trajectories of change in body mass index (BMI) and depressive symptoms during inpatient treatment, examine clinical predictors and outcomes, and test ...
Matteo Martini, Mie Sedoc Jørgensen, Cristiano Dani, Anne Bryde Christensen, Magnus Sjögren, Nadia Micali   +5 more
wiley   +1 more source

Upregulation of PD-1/PD-L1 and downregulation of immune signaling pathways lead to more severe visceral leishmaniasis in undernutrition mice

Parasites & Vectors
Background Leishmaniasis is mainly prevalent in tropical and subtropical developing countries, where chronic undernutrition often co-exists. Undernutrition is reported to promote the progression of leishmaniasis, but its immune mechanisms have not been ...
Jinlei He, Jianhui Zhang, Xuechun Liao, Yuying Xiao, Jiao Li, Zhiwan Zheng, Dali Chen, Jianping Chen   +7 more
doaj   +1 more source