Results 91 to 100 of about 127,482 (308)

Heterogeneity in BMI Percentile and Weight Status Among Asian American Youth

AJPM Focus
Introduction: There are important and understudied health differences among subgroups of Asian Americans. The authors examined differences in BMI percentile and body weight status among Asian American youth. Methods: The authors conducted a retrospective
Darcy M. Van Deventer, BS, Margo A. Sidell, SCD, Catherine Lee, PhD, Deborah R. Young, PhD, Monique M. Hedderson, PhD, Deborah A. Cohen, MD, MPH, Emily F. Liu, MPH, Lee J. Barton, MS, Galina Inzhakova, MPH, Bing Han, PhD   +9 more
doaj   +1 more source

Assessment of nutritional status by composite index of anthropometric failure (CIAF): a study among preschool children of Sagar Block, South 24 Parganas District, West Bengal, India

Anthropological Review, 2018
Being a developing nation, rural India is still facing a serious health problem in form of undernutrition particularly among young children. To optimize this problem, the Central Government has been operating a nationwide nutritional intervention ...
Biswas Sadaruddin, Giri Som Prasad, Bose Kaushik   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Study on Health Status of Urban School Children (7-18 Years): A School Based Cross Sectional Study

National Journal of Community Medicine, 2017
Background: School age is considered as a dynamic period of growth and development because children undergo physical, mental, emotional and social changes.
Jai P Singh, Atul Kumar Singh
doaj  

Nutritional Status of Children and its Relation to Maternal Factors: An Endeavor Toward Better-Nourished Western Rural India

Indian Journal of Community Medicine
Introduction: Malnutrition has a direct impact on infant mortality rate and under-five mortality rates, which are prime indicators of the health status of a country. COVID-19 has also substantially affected the nutritional status of children.
Krishna M. Jasani, Vibha V. Gosalia, Shobha V. Misra   +2 more
doaj   +1 more source

Using weight-for-age for predicting wasted children in Cameroon

The Pan African Medical Journal, 2013
INTRODUCTION: The equipment for taking body weights (scales) are more frequently used in Cameroon health centres than measuring boards for heights.
Georges Nguefack-Tsague, Agatha Tanya Nguti Kien, Charles Ntungwen Fokunang   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Association between body mass index and survival after hematopoietic stem cell transplantation [PDF]

The Korean Journal of Internal Medicine
Background/Aims The unclear relationship between body mass index (BMI) and post-hematopoietic stem cell transplantation (HSCT) mortality was investigated, including the impact of metabolic diseases.
Han-Sang Baek, Jong Hyuk Lee, Joonyub Lee, Seung-Hwan Lee, Gi June Min, Sung-Soo Park, Silvia Park, Sung-Eun Lee, Byung-Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Chang-Ki Min, Seok-Goo Cho, Jong Wook Lee, Jae-Ho Yoon   +16 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source