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The relationship between semen factors and unexplained recurrent spontaneous abortion
Clinica Chimica Acta, 2020The male factor may contribute to unexplained recurrent spontaneous abortion (URSA). The relationship between semen factors and URSA is largely unknown. The analysis of metabolomics which is broadly acknowledged as the omics closest to the phenotype is suitable for providing assistance in the semen parameters analysis.We conducted a study including ...
Xinyue, Zhang +9 more
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T regulatory markers expression in unexplained recurrent spontaneous abortion
Objective: To evaluate expression of glucocorticoid-induced tumor necrosis factor receptor (GITR), cytotoxic T lymphocyte-Associated antigen 4 (CTLA-4) and IL-10 in peripheral blood mononuclear cells (PBMCs) of 20 women with unexplained recurrent ...
Seyed Abdolrahim Rezaee +2 more
exaly +1 more source
Immunity to Cytomegalovirus in Women With Unexplained Recurrent Spontaneous Abortion
American Journal of Reproductive Immunology and Microbiology, 1986ABSTRACT: Humoral and cellular immunity to cytomegalovirus (CMV) has been assessed in women suffering unexplained recurrent spontaneous abortions (RSA). A significantly lower prevalence of serum anti‐CMV antibodies was observed for RSA women compared with either their male partners or age‐matched female controls, unlike for serum antibodies to Herpes ...
J J, Radcliffe +3 more
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Prothrombotic state of patients with unexplained recurrent spontaneous abortion
International Journal of Gynecology & Obstetrics, 2015To determine the effect of aspirin and low-molecular-weight heparin (LMWH) for women affected by recurrent spontaneous abortion (RSA).The present prospective observational study included women with RSA (≥ 2 previous spontaneous abortions) and those without a history of RSA attending Ren Ji Hospital, Shanghai, China, between March 2011 and March 2014. D-
Xuefeng, Lu +5 more
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Sperm DNA fragmentation in couples with unexplained recurrent spontaneous abortions
Andrologia, 2012The aim of the present study was to evaluate the degree of sperm DNA fragmentation in couples with idiopathic recurrent spontaneous abortion (RSA) and in those with no history of infertility or abortion. In this cohort study, 30 couples with RSA and 30 fertile couples as control group completed the demographic data questionnaires, and their semen ...
N, Khadem +4 more
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T regulatory markers expression in unexplained recurrent spontaneous abortion
The Journal of Maternal-Fetal & Neonatal Medicine, 2015To evaluate expression of glucocorticoid-induced tumor necrosis factor receptor (GITR), cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and IL-10 in peripheral blood mononuclear cells (PBMCs) of 20 women with unexplained recurrent spontaneous abortion (URSA) compared to 20 normal non-pregnant women (NNP) during luteal phase in the window of ...
Bita, Saifi +9 more
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Potential involvement of placental AhR in unexplained recurrent spontaneous abortion
Reproductive Toxicology, 2016Recurrent spontaneous abortion (RSA) is a common complication of pregnancy. Recent studies have demonstrated that the aryl hydrocarbon receptor (AhR) might play important roles in establishing and maintaining early pregnancy. In this study, we found that placental AhR protein levels were significantly lower and placental CYP1A1 mRNA levels were higher ...
Y Wu +9 more
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Lack of evidence for a role of HLA-DP in unexplained recurrent spontaneous abortion
Transfusion Clinique et Biologique, 1995Using the "Polymerase Chain Reaction-Sequence Specific Oligoprobes" (PCR-SSOp) technique, we studied the HLA-DPB locus in both partners of 59 couples with a history of three spontaneous abortions, and of 38 control couples in order to determine the role of this centromeric region of the major histocompatibility complex (MHC) in the immune reaction ...
P, Sagot +5 more
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Archives of Gynecology and Obstetrics, 2015
Abnormal natural killer (NK) cell activity has been suggested to be a high-risk factor associated with unexplained recurrent spontaneous abortion (URSA). Intralipid, like immunoglobulin, is able to lower the activity of NK cells, which has been reported to be useful for improving URSA outcomes in pregnancy.
Lili, Meng +9 more
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Abnormal natural killer (NK) cell activity has been suggested to be a high-risk factor associated with unexplained recurrent spontaneous abortion (URSA). Intralipid, like immunoglobulin, is able to lower the activity of NK cells, which has been reported to be useful for improving URSA outcomes in pregnancy.
Lili, Meng +9 more
openaire +2 more sources
Journal of Proteomics, 2023
Unexplained recurrent spontaneous abortion (URSA) seriously affects female reproductive health, causing a great burden to patients both physically and mentally. Endometrial decidualization plays an important role in pregnancy, and impaired decidualization is an essential cause of URSA, but the cause of the damage is still poorly understood.
Lei, Zhang +10 more
openaire +2 more sources
Unexplained recurrent spontaneous abortion (URSA) seriously affects female reproductive health, causing a great burden to patients both physically and mentally. Endometrial decidualization plays an important role in pregnancy, and impaired decidualization is an essential cause of URSA, but the cause of the damage is still poorly understood.
Lei, Zhang +10 more
openaire +2 more sources

