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The ESR1 gene in unexplained recurrent spontaneous abortion [PDF]
Systems Biology in Reproductive Medicine, 2014 Recurrent spontaneous abortion (RSA) is a health problem that affects nearly 1% of fertile couples. However, the underlying etiology and mechanism(s) remain elusive. The aim of this study was to investigate estrogen receptor (ESR) 1 gene polymorphisms for risk association of unexplained recurrent spontaneous abortion (URSA) in the Chinese Han ...
Sirui Zhou, Binbin Wang
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Potential role of circulating microRNAs as a biomarker for unexplained recurrent spontaneous abortion [PDF]
Fertility and Sterility, 2016 To compare circulating microRNA (miRNA) profiles between unexplained recurrent spontaneous abortion (URSA) and normal early pregnancies (NEP) and to evaluate the potential role of circulating miRNA as a biomarker for URSA.Laboratory study using human plasma samples.Special hospital and research institutes.From September 2012 to April 2013, samples of ...
Weibing Qin
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Analysis of the risk factors in patients with unexplained recurrent spontaneous abortion
American Journal of Reproductive Immunology, 2023AbstractProblemWe aimed to explore the risk factors in patients with unexplained recurrent spontaneous abortion (URSA) and to provide a basis for clinically targeted therapy.Method of studyThis case‐control study comprised 202 patients with URSA treated at our hospital and 115 women in early pregnancy with a normal birth history during the same period.
Ming‐Ming Li +4 more
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Differentially expressed genes implicated in unexplained recurrent spontaneous abortion
International Journal of Biochemistry and Cell Biology, 2007Recurrent spontaneous abortion occurs in approximately 3% of women with diagnosed pregnancies. The etiology in approximately 40% of recurrent spontaneous abortion is unexplained. To elucidate unexplained recurrent spontaneous abortion at the molecular level, we systemically identified differentially expressed genes during implantation window period in ...
Inju Park, Cecil Han, Chunghee Cho
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The relationship between semen factors and unexplained recurrent spontaneous abortion
Clinica Chimica Acta, 2020The male factor may contribute to unexplained recurrent spontaneous abortion (URSA). The relationship between semen factors and URSA is largely unknown. The analysis of metabolomics which is broadly acknowledged as the omics closest to the phenotype is suitable for providing assistance in the semen parameters analysis.We conducted a study including ...
Xinyue, Zhang +9 more
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Immunity to Cytomegalovirus in Women With Unexplained Recurrent Spontaneous Abortion
American Journal of Reproductive Immunology and Microbiology, 1986ABSTRACT: Humoral and cellular immunity to cytomegalovirus (CMV) has been assessed in women suffering unexplained recurrent spontaneous abortions (RSA). A significantly lower prevalence of serum anti‐CMV antibodies was observed for RSA women compared with either their male partners or age‐matched female controls, unlike for serum antibodies to Herpes ...
J J, Radcliffe +3 more
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Prothrombotic state of patients with unexplained recurrent spontaneous abortion
International Journal of Gynecology & Obstetrics, 2015To determine the effect of aspirin and low-molecular-weight heparin (LMWH) for women affected by recurrent spontaneous abortion (RSA).The present prospective observational study included women with RSA (≥ 2 previous spontaneous abortions) and those without a history of RSA attending Ren Ji Hospital, Shanghai, China, between March 2011 and March 2014. D-
Xuefeng, Lu +5 more
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Allogenic Lymphocyte Immunotherapy for Unexplained Recurrent Spontaneous Abortion: A Meta‐Analysis
American Journal of Reproductive Immunology, 2016Allogenic lymphocyte immunotherapy (LIT) as a treatment for unexplained recurrent spontaneous abortion (URSA) is still controversial due to the lack of enough controls to evaluate its effectiveness. Eighteen randomized, placebo‐controlled trials with LIT for URSA were included in the meta‐analysis.
Haijing Xu +2 more
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T regulatory markers expression in unexplained recurrent spontaneous abortion
The Journal of Maternal-Fetal & Neonatal Medicine, 2015To evaluate expression of glucocorticoid-induced tumor necrosis factor receptor (GITR), cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and IL-10 in peripheral blood mononuclear cells (PBMCs) of 20 women with unexplained recurrent spontaneous abortion (URSA) compared to 20 normal non-pregnant women (NNP) during luteal phase in the window of ...
Bita, Saifi +9 more
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Sperm DNA fragmentation in couples with unexplained recurrent spontaneous abortions
Andrologia, 2012The aim of the present study was to evaluate the degree of sperm DNA fragmentation in couples with idiopathic recurrent spontaneous abortion (RSA) and in those with no history of infertility or abortion. In this cohort study, 30 couples with RSA and 30 fertile couples as control group completed the demographic data questionnaires, and their semen ...
N, Khadem +4 more
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