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Integrated analysis of lncRNA and mRNA expression profiles in patients with unexplained recurrent spontaneous abortion

American Journal of Reproductive Immunology, 2023
Abstract Problem Unexplained recurrent spontaneous abortion (URSA) is one of the most frustrating and confounding conditions in reproductive medicine, and its exact pathogenesis has not been clearly established. Method of study In this study, we used RNA sequencing to characterize the mRNA and lncRNA expression profiles in peripheral blood. Thereafter,
Mengxuan Du
exaly   +2 more sources

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Immunopharmacological Properties of VitD3: 1, 25VitD3 Modulates Regulatory T Cells and Th17 Cells and the Cytokine Balance in PBMCs from Women with Unexplained Recurrent Spontaneous Abortion (URSA)

Current Molecular Pharmacology, 2022
Background: VitD3 may contribute to a successful pregnancy through modulation of immune responses. Therefore, VitD3 deficiency may have a role in the immunopathogenesis of unexplained recurrent spontaneous abortion (URSA). However, the mechanisms of immunomodulatory actions of VitD3 in decreasing the risk of recurrent spontaneous abortion have not ...
Jiefan Gao, Li Wang, Lei Bu, Yangyang Song, Xiao Huang, Jing Zhao   +5 more
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Associations of Paternal Seminal Plasma Metals with their Spouses’ Unexplained Recurrent Spontaneous Abortion (URSA) Risk and the Potential Mediating Role of Oxidative Stress

Biological Trace Element Research
Unexplained recurrent spontaneous abortion (URSA) is a prevalent reproductive issue but its etiology remains obscure. Male exposure to environmental chemicals is suggested to elevate URSA risk in female partners. Herein, a case-control design set out to investigate associations between metal levels in human seminal plasma with URSA risk, plus to ...
Hanyan, Xi, Rui, Yang, Huaqiong, Bao, Huiru, Li, Youzhu, Li, Francis L, Martin, Wei, Chen, Liang, Chen, Yan, Sun, Yan-Yang, Lu, Qingyu, Huang, Meiping, Tian   +11 more
openaire   +2 more sources

miR-146a-5p enhances embryo survival in unexplained recurrent spontaneous abortion by promoting M2 polarization of decidual macrophages

International Immunopharmacology, 2022
Qu Zheng
exaly  

Significance of the ratio interferon‐γ/interleukin‐4 in early diagnosis and immune mechanism of unexplained recurrent spontaneous abortion

International Journal of Gynecology and Obstetrics, 2021
Yizhi Peng, Sheng Yin, Min Wang
exaly  

Association of bisphenol A or bisphenol S exposure with oxidative stress and immune disturbance among unexplained recurrent spontaneous abortion women

Chemosphere, 2020
Fan Liang, Xiaona Huo, Yan Feng
exaly  

Potential role of circulating microRNAs as a biomarker for unexplained recurrent spontaneous abortion

Fertility and Sterility, 2016
Weibing Qin
exaly  

Allogenic Lymphocyte Immunotherapy for Unexplained Recurrent Spontaneous Abortion: A Meta‐Analysis

American Journal of Reproductive Immunology, 2016
Haijing Xu, Xiaomin Kang, Tongfei Wang   +2 more
exaly  

Study on the Relationship Between Th17 Cells and Unexplained Recurrent Spontaneous Abortion

American Journal of Reproductive Immunology, 2011
Yu-Sheng Liu, Li-Min Wu
exaly  

Changes of CD4+CD25high regulatory T cells and FOXP3 expression in unexplained recurrent spontaneous abortion patients

Fertility and Sterility, 2010
Shanshan Mei, Jianping Tan, Hui Chen
exaly