Results 61 to 70 of about 1,806,850 (248)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Resolución del Consejo de 12 de febrero de 2001 sobre la aplicación de los sistemas nacionales de fijación del precio de los libros [PDF]
, 2001 El Consejo de la Unión Europea invita a la Comisión, a tener en cuenta, al aplicar las normas en materia de competencia y de libre circulación de competencias, el valor cultural particular del libro y su importancia para el fomento de la diversidad ...
Consejo de la Unión Europea
core
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
¿Optimismo o pesimismo por los resultados del movimiento unionista?
Estudios Eclesiásticos, 1959 Algunas autoridades de las diferentes Iglesias cristianas se reunieron en Ginebra en octubre de 1955 con el anhelo común de buscar todo lo que nos une. La división de los cristianos supone uno de los mayores obstáculos para los que no creen. En el último
Ignacio Riudor
doaj
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Inteligencia emocional y procrastinación académica en estudiantes universitarios en Perú
Ciencias PsicológicasEl objetivo de este estudio fue analizar la relación entre la Inteligencia Emocional (IE) y la Procrastinación Académica (PA) en estudiantes universitarios y generar un modelo predictivo. Este estudio tiene un enfoque cuantitativo y de diseño predictivo
Samuel Chavez-Fernandez +3 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source