Results 131 to 140 of about 28,605,013 (311)
, 2017 166 p.This analysis of the Greek health system reviews developments in itsorganization and governance, health financing, health care provision,health reforms and health system performance.
Economou, Charalampos +5 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A crise mundial de 2008 e o golpe do capital na política de saúde no Brasil
Saúde em DebateRESUMO O objetivo do artigo foi analisar a conjuntura posterior às eleições presidenciais de 2014, discutindo possíveis relações com a crise econômica mundial e com os desdobramentos do golpe de 2016 na saúde.
Carmen Fontes de Souza Teixeira +1 more
doaj +1 more source
, 2009 162 p.The Health Systems in Transition (HiT) profiles are country-based reports that provide a detailed description of a health system and of policyinitiatives in progress or under development.
Tatara, Kozo +5 more
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Saúde em DebateO artigo trata das formas de fazer a regionalização da saúde, objetivando analisar as dimensões da institucionalidade e governança na sua gestão. Fez-se pesquisa qualitativa retrospectiva em base documental (1995-2009).
Ruth Terezinha Kehrig +2 more
doaj +1 more source
[The territorialization of Primary Health Care of the Brazilian Unified Health System].
Ciencia & saude coletiva, 2021 The territorialization of Primary Health Care is an important social and political process for the implementation of the constitutional principles of the Unified Health System (SUS) in Brazil. The SUS is essentially a nationwide care project, organized into regionalized care networks, with its command center in Primary Health Care (PHC).
openaire +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2006 247 p.The Health Systems in Transition (HiT) series provide detailed descriptions of health systems in the countries of the WHO European Region as well as some additional OECD countries.
Riesberg, Annette +4 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source