Results 141 to 150 of about 145,307 (258)

Effect of storytelling on learning about the institutionalization of Unified Health System: randomized controlled trial. [PDF]

open access: yesRev Bras Enferm
Silva ÁDME   +5 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Unified System State: Diagnostic Metrics for System Health

open access: yes
Unified System State: Diagnostic Metrics for System Health introduces a practitioner-facing model for system health that complements SLO-based alerting with behavioral context. The paper presents two core metrics: Directional Momentum (DM), a time-series metric integrating momentum magnitude with an explicit oscillation penalty to detect yo-yo behavior,
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Social Determinants of Health: the constitutional instituted in the Unified Health System

open access: yes, 2018
Objetivo: Compreender a relação entre o instituído constitucional sobre os determinantes sociais da saúde e a vivência urbana num território em situação de vulnerabilidade social.Métodos: Baseou-se na abordagem qualitativa, com utilização de grupo focal e de entrevista semi estruturada, aplicados a 45 participantes.
Ribeiro, Kelen Gomes   +2 more
openaire   +1 more source

Hospitalizations for congenital infections in Brazil's unified health system: nationwide trends and regional disparities, 2008-2024. [PDF]

open access: yesAntimicrob Steward Healthc Epidemiol
Callado GY   +5 more
europepmc   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Health Inequalities: A Challenge for the Brazilian Unified Health System (SUS)

open access: yes
Health inequalities represent one of the greatest challenges for public health systems worldwide, especially in countries with significant socioeconomic heterogeneity such as Brazil. These inequalities are evident in access to, quality of, and outcomes from health services, reflecting the profound social, economic, and cultural disparities that impact ...
openaire   +1 more source

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