Results 151 to 160 of about 28,605,013 (311)

Israel: health system review

, 2015
212 p.Israel is a small country, with just over 8 million citizens and a modernmarket-based economy with a comparable level of gross domestic productper capita to the average in the European Union.
Rosen, Bruce, Waitzberg, Ruth, Merkur, Sherry, European Observatory on Health Systems and Policies, World Health Organization. Regional Office for Europe   +4 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Latvia: health system review

, 2019
165 p.This analysis of the Latvian health system reviews recent developments in organization and governance, health financing, health care provision, health reforms and health system performance.
Scarpetti, Giada, Behmane, Daiga, Dudele, Alina, Villerusa, Anita, Misins, Janis, European Observatory on Health Systems and Policies, Mozgis, Dzintars, Klavina, Kristine, World Health Organization. Regional Office for Europe   +8 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Belgium: health system review

, 2007
171 p.The Health Systems in Transition (HiT) profiles are country-based reports that provide a detailed description of a health system and of policyinitiatives in progress or under development.
Merkur, Sherry, Palm, Willy, Jemiai, Nadia, Corens, Dirk, European Observatory on Health Systems and Policies, World Health Organization. Regional Office for Europe   +5 more
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Georgia: health system review

, 2017
xx, 90 p.This analysis of the Georgian health system reviews developments in its organization and governance, health financing, health care provision, health reforms and health system performance.
Richardson, Erica, European Observatory on Health Systems and Policies, World Health Organization. Regional Office for Europe, Berdzuli, Nino   +3 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Azerbaijan: health system review

, 2010
115 p.The Health Systems in Transition (HiT) profiles are country-based reportsthat provide a detailed description of a health system and of policyinitiatives in progress or under development.
Ibrahimova, Aybaniz, Ibrahimov, Fuad, Richardson, Erica, European Observatory on Health Systems and Policies, Kehler, Jenni, World Health Organization. Regional Office for Europe   +5 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source