Results 161 to 170 of about 2,337,724 (336)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

O desafio da gestão de equipamentos médico-hospitalares no Sistema Único de Saúde

open access: yesSaúde em Debate
O estudo analisou as políticas de gestão de equipamentos médico-hospitalares adotadas pelo Ministério da Saúde para o Sistema Único de Saúde. Realizou-se uma análise documental das publicações do Ministério da Saúde e uma análise de dados do Cadastro ...
Aline Silva Amorim   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The rehabilitation workforce in Brazil

open access: yesArchives of Public Health
Background The surge in individuals facing functional impairments has heightened the demand for rehabilitation services. Understanding the distribution of the rehabilitation workforce is pivotal for effective health system planning to address the ...
Taciana Rocha dos Santos Sixel   +5 more
doaj   +1 more source

Bringing the Good Food Purchasing Program to Buffalo [PDF]

open access: yes, 2017
An investigation of potential environmental stakeholder participation in the Good Food Purchasing Program. The objective of this report is to investigate the GFPP’s value of environmental sustainability, to assess if this value is compatible with those ...
Gilbert, Jessica
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Partnering with Public Schools to End Family Homelessness in San Francisco [PDF]

open access: yes, 2016
Hamilton Family Center (HFC) is a nonprofit organization with the mission of ending family homelessness in the San Francisco Bay Area. As part of their initiative to end family homelessness in San Francisco by 2019, HFC partnered with the San Francisco ...

core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Integrated System Health Management (ISHM) and Autonomy [PDF]

open access: yes
Systems capabilities on ISHM (Integrated System Health Management) and autonomy have traditionally been addressed separately. This means that ISHM functions, such as anomaly detection, diagnostics, prognostics, and comprehensive system awareness have ...
Figueroa, Fernando, Walker, Mark G.
core   +1 more source

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