Results 181 to 190 of about 28,605,013 (311)

Unified System State: Diagnostic Metrics for System Health

open access: yes
Unified System State: Diagnostic Metrics for System Health introduces a practitioner-facing model for system health that complements SLO-based alerting with behavioral context. The paper presents two core metrics: Directional Momentum (DM), a time-series metric integrating momentum magnitude with an explicit oscillation penalty to detect yo-yo behavior,
openaire   +2 more sources

Finland: health system review

open access: yes, 2019
166 p.This analysis of the Finnish health system reviews developments in its organization and governance, financing, provision of services, health reforms and health system performance. Finland is a welfare state with a high standard of social and living
Rechel, Bernd   +9 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Estonia: health system review

open access: yes, 2013
196 p.This analysis of the Estonian health system reviews recent developmentsin organization and governance, health financing, health care provision,health reforms and health system performance.Without doubt, the main issue has been the 2008 financial ...
Reinap, Marge   +7 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Organização da demanda de um Centro de Especialidades Odontológicas

open access: yesRevista de Odontologia da UNESP
INTRODUÇÃO: A Atenção Secundária em saúde bucal no Brasil ainda é um assunto pouco pesquisado. OBJETIVO: Analisar a resolubilidade dos serviços odontológicos do Sistema Único de Saúde, com base na referência para a atenção secundária e a ...
Nemre Adas Saliba   +4 more
doaj  

Health Inequalities: A Challenge for the Brazilian Unified Health System (SUS)

open access: yes
Health inequalities represent one of the greatest challenges for public health systems worldwide, especially in countries with significant socioeconomic heterogeneity such as Brazil. These inequalities are evident in access to, quality of, and outcomes from health services, reflecting the profound social, economic, and cultural disparities that impact ...
openaire   +1 more source

Greece: health system review

open access: yes, 2010
xxii, 177 p.The Health Systems in Transition (HiT) country profiles provide an analytical description of each health system and of policy initiatives in progress or under development. They aim to provide relevant comparative information to support policy-
Economou, Charalambos   +2 more
core  

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