Results 51 to 60 of about 1,112,952 (328)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Module architecture "Electronic document management system on students" [PDF]

, 2016
Software system architecture represented as shown in the diagram components, described in a unified modeling language ...
Капустина, Светлана Сергеевна, Кузнецов, Дмитрий Юрьевич   +1 more
core  

A framework for an integrated unified modeling language

Frontiers of Information Technology & Electronic Engineering, 2016
The unified modeling language (UML) is one of the most commonly used modeling languages in the software industry. It simplifies the complex process of design by providing a set of graphical notations, which helps express the objectoriented analysis and ...
M. Alshayeb, Nasser Khashan, Sajjad Mahmood   +2 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Unified Modeling Language Quantitative Measures Based on a Behavioural Model [PDF]

مجلة التربية والعلم
Behavioral diagrams in Unified Modeling Language reflect the interaction between system components and give a comprehensive description and visualization of the system during the design phase. One of the most important behavioral diagrams is the sequence
Marwah Dabdawb
doaj   +1 more source

Towards an Information Retrieval Theory of Everything [PDF]

, 2009
I present three well-known probabilistic models of information retrieval in tutorial style: The binary independence probabilistic model, the language modeling approach, and Google's page rank.
Hiemstra, Djoerd
core   +2 more sources

Software system architecture for corporate user support [PDF]

, 2017
In this article, several existing ready-to-use solutions for the HelpDesk are reviewed. Advantages and disadvantages of these systems are identified. Architecture of software solution for a corporate user support system is presented in a form of the use ...
Kuznetsov, Dmitriy Yurievich, Sukhopluyeva, Viktoriia Sergeevna   +1 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Concurrency coverage criteria for activity diagrams

IET Software, 2021
Existing coverage criteria for Unified Modeling Language (UML)‐based system design have used mostly structural constructs and sequential‐behavioural coverage criteria. However, concurrent‐behavioural coverage criteria are not sufficiently explored.
Mahesh Shirole, Rajeev Kumar
doaj   +1 more source