Results 71 to 80 of about 1,152,162 (330)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Semantic and Structural Difficulties with the Unified Modeling Language Use-Case Notation version 1.3 [PDF]
, 1999 A case study was undertaken to examine and apply the UML use-case notation version 1.3. This study shows that the notation is open to interpretation and the semantics of the use-case relationships are confusing. The attempt to bolt on the object-oriented
Cox, Karl, Phalp, Keith T.
core
An executable software architecture model for response time and reliability assessment [PDF]
Management Science Letters, 2014 With the increasing use of the Unified Modeling Language (UML) diagrams to describe the software’s architecture and the importance of evaluating nonfunctional requirements at the level of software architecture, creating an executable model from these ...
Zahra Norouzi, Ali Harounabadi
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Ontologies and Unified Modeling Language: an approach to representation of domains of knowledge [PDF]
, 2009 This article emphasizes the use of Unified Modeling Language, UML in the specification of models based on ontologies in the representation of domains of knowledge, emphasizing the importance of semantic and of treatment of standardized language so the ...
Demarques, Eliana Antonia +3 more
core
Analysis of System-Failure Rate Caused by Soft-Errors using a UML-Based Systematic Methodology in an SoC [PDF]
, 2007 This paper proposes an analytical method to assess the soft-error rate (SER) in the early stages of a System-on-Chip (SoC) platform-based design methodology.
Benso, Alfredo +6 more
core +2 more sources
Industria: Jurnal Teknologi dan Manajemen Agroindustri, 2018 Abstrak Penggunaan varietas padi unggul adalah inovasi teknologi yang mudah diadopsi untuk peningkatan produktivitas padi. Tanpa program benih bersubsidi, banyak petani tidak menggunakan benih padi berkualitas/bersertifikat karena tidak tersedianya ...
Yogi Purna Rahardjo +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
UML-based navigational design approach for modeling complex interactions in web applications [PDF]
, 2015 Different complex interactions in web applications has raised new concerns on the behavior modeling approach. Web designers should designate complex interactions in web applications and provide a clear view in the design model stages.
Abdullah, Rusli +3 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source