Results 61 to 70 of about 11,868,797 (285)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Artificial ecosystem optimized neural network controlled unified power quality conditioner for microgrid application

open access: yesEnergy Informatics, 2023
Unified power quality conditioner is chiefly employed to offer power quality improvement, especially in grid connected mode of operation in microgrid applications.
Rajeev Ratnakaran   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Study of Unified Power Quality Conditioner for Power Quality Improvement

open access: yesInternational Journal Of Engineering And Computer Science, 2016
These In a powers system network there are many problems related to power quality. So to improve power quality of a system we use different devices such as active power filters. Active power filters are classified into two types that is Shunt Active Power Filter (APF) and Series Active Power Filter (APF) and combination of both is known as UPQC ...
openaire   +1 more source

Study of Unified Power Quality Conditioner for Power Quality Improvement [PDF]

open access: yes, 2015
In a powers system network there are many problems related to power quality. So to improve power quality of a system we use different devices such as active power filters.
Sinku, Rajiv Kumar
core  

IMPROVEMENT OF POWER QUALITY USING SOLAR PV INTEGRATED UNIFIED POWER QUALITY CONDITIONER

open access: yes, 2018
This paper presents, the use of unified power quality conditioner (UPQC) to eliminate power quality issues. The solar PV panel with boost converter is integrated at the DC-link of UPQC.
Swaroopa S. Bhosale, Y. N. Bhosale
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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