Results 51 to 60 of about 1,282,961 (279)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Uniform Bounds for Sampling Expansions
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
A Uniform Asymptotical Upper Bound for the Variance of a Random Polytope in a Simple Polytope
The present paper contains a sketch of the proof of an upper bound for the variance of the number of hyperfaces of a random polytope when the mother body is a simple polytope.
A. Magazinov
doaj +3 more sources
Spectral gap lower bound for the one-dimensional fractional Schr\"odinger operator in the interval
We prove the uniform lower bound for the difference $\lambda_2 - \lambda_1$ between first two eigenvalues of the fractional Schr\"odinger operator, which is related to the Feynman-Kac semigroup of the symmetric $\alpha$-stable process killed upon leaving
Kaleta, Kamil
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
"Regulation of bound acrylonitrile content of nitrile rubber with low acrylonitrile content"
The factors affecting the bound acrylonitrile content of NBR product during the polyme-rization process were investigated, including monomer reactivity ratio, monomer conversion, monomer concentration, and polymerization temperature and pressure, the ...
HU Yu-lin, WANG Yong-feng, ZHONG Qi-lin, ZHAO Zhi-chao, SHAO Wei
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The paper shows that the distribution of the normalized least squares estimator of the drift parameter in the fractional Ornstein-Uhlenbeck process observed over [0, T] converges to the standard normal distribution with an uniform optimal error bound of ...
Jaya P. N. Bishwal
doaj +1 more source
Warped Tori with Almost Non-Negative Scalar Curvature
For sequences of warped product metrics on a $3$-torus satisfying the scalar curvature bound $R_j \geq -\frac{1}{j}$, uniform upper volume and diameter bounds, and a uniform lower area bound on the smallest minimal surface, we find a subsequence which ...
Allen, Brian +4 more
core +1 more source

