Results 71 to 80 of about 1,282,961 (279)
Regulating Constraint-Following Bound for Uncertain Mechanical Systems: An Indirect Control Approach
IEEE Access, 2020 This paper proposes an indirect approach of constraint-following control for mechanical systems with (possibly fast) time-varying uncertainty. It proposes to design controller for the system to render bounded constraint-following error.
Qinqin Sun +3 more
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Filtrations of dc-weak eigenforms
, 2017 The notions of strong, weak and dc-weak eigenforms mod $p^n$ was introduced and studied by Chen, Kiming and Wiese. In this work, we prove that there can be no uniform weight bound (that is, depending only on $p$, $n$) on dc-weak eigenforms mod $p^n$ of ...
Rustom, Nadim
core +1 more source
New Non-Uniform Lower Bounds for Uniform Classes.
, 2016 We strengthen the nondeterministic hierarchy theorem for non-deterministic polynomial time to show that the lower bound holds against sub-linear advice. More formally, we show that for any constants d and d' such that 1 <= d < d', and for any time-constructible bound t=o(n^d), there is a language in NTIME(n^d) which is not in NTIME(t)/n^{1/d ...
Lance Fortnow, Rahul Santhanam
openaire +3 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
An Algorithmic Approach to Uniform Lower Bounds.
Electron. Colloquium Comput. Complex., 2023 We propose a new family of circuit-based sampling tasks, such that non-trivial algorithmic solutions to certain tasks from this family imply frontier uniform lower bounds such as "NP is not in uniform ACC⁰" and "NP does not have uniform polynomial-size depth-two threshold circuits".
openaire +4 more sources
Uniform Convergence Bounds for Codec Selection
CoRR, 2018 We frame the problem of selecting an optimal audio encoding scheme as a supervised learning task. Through uniform convergence theory, we guarantee approximately optimal codec selection while controlling for selection bias. We present rigorous statistical guarantees for the codec selection problem that hold for arbitrary distributions over audio ...
Clayton Sanford +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source