Results 81 to 90 of about 1,679,233 (282)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Holographic limitations and corrections to quantum information protocols

open access: yesPhysical Review Research
We discuss the limitations imposed on entanglement distribution, quantum teleportation, and quantum communication by holographic bounds, such as the Bekenstein bound and Susskind's spherical entropy bound. For continuous-variable (CV) quantum information,
Stefano Pirandola
doaj   +1 more source

Bandwidth Efficiency Maximization for Single-Cell Massive Spatial Modulation MIMO: An Adaptive Power Allocation Perspective

open access: yesIEEE Access, 2017
The concept of massive spatial modulation aided multiple-input multiple-output (SM-MIMO) systems, where the base station (BS) is equipped with a large number of antennas and simultaneously serves several multi-antenna users that employ SM for their ...
Longzhuang He   +3 more
doaj   +1 more source

Sharp Bounds for Generalized Uniformity Testing

open access: yesCoRR, 2017
We study the problem of generalized uniformity testing \cite{BC17} of a discrete probability distribution: Given samples from a probability distribution $p$ over an {\em unknown} discrete domain $\mathbfΩ$, we want to distinguish, with probability at least $2/3$, between the case that $p$ is uniform on some {\em subset} of $\mathbfΩ$ versus $ε$-far, in
Diakonikolas, Ilias   +2 more
openaire   +6 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Uniform Bounds for Limited Sets and Applications to Bounding Sets.

open access: yesMATHEMATICA SCANDINAVICA, 2000
A set \(D\) in a Banach space \(E\) is called limited if every \(w^\ast\)-null sequence \((\phi_k)_k\) in the dual space \(E^\ast\) converges uniformly on \(D\). Relatively compact sets are limited, and the converse happpens when \(E\) is separable [see \textit{J.
openaire   +2 more sources

An Algorithmic Approach to Uniform Lower Bounds.

open access: yesElectron. Colloquium Comput. Complex., 2023
We propose a new family of circuit-based sampling tasks, such that non-trivial algorithmic solutions to certain tasks from this family imply frontier uniform lower bounds such as "NP is not in uniform ACC⁰" and "NP does not have uniform polynomial-size depth-two threshold circuits".
openaire   +4 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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