Results 61 to 70 of about 1,679,233 (282)

On the Kolmogorov Distance for the Least Squares Estimator in the Fractional Ornstein-Uhlenbeck Process

open access: yesEuropean Journal of Mathematical Analysis, 2023
The paper shows that the distribution of the normalized least squares estimator of the drift parameter in the fractional Ornstein-Uhlenbeck process observed over [0, T] converges to the standard normal distribution with an uniform optimal error bound of ...
Jaya P. N. Bishwal
doaj   +1 more source

(Quasi)‐uniformities on the set of bounded maps [PDF]

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1993
From real analysis it is known that if a sequence {fn,    n ∈ ℕ} of real‐valued functions defined and bounded on X ⊂ ℝ converges uniformly to f, then f is also bounded and the sequence {fn,    n ∈ ℕ}. In the present paper we generalize results as the above using (quasi)‐uniform structures.
openaire   +3 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

"Regulation of bound acrylonitrile content of nitrile rubber with low acrylonitrile content"

open access: yesHecheng xiangjiao gongye, 2023
 The factors affecting the bound acrylonitrile content of NBR product during the polyme-rization process were investigated, including monomer reactivity ratio, monomer conversion, monomer concentration, and polymerization temperature and pressure, the ...
HU Yu-lin, WANG Yong-feng, ZHONG Qi-lin, ZHAO Zhi-chao, SHAO Wei
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Randi´c Matrix and Randi´c Energy of Uniform Hypergraphs [PDF]

open access: yesMathematics Interdisciplinary Research
‎The Randi´c matrix $R=[r_{ij}]$ of a graph $ G=(V,E) $ was defined as $r_{ij}=\frac{1}{\sqrt{d_id_j}}$ if vertices $v_i$ and $v_j$ are adjacent and $r_{ij}=0$ otherwise‎, ‎where $d_i$ is the degree of the vertex $v_i\in V$‎.
Gholam Hassan Shirdel   +2 more
doaj   +1 more source

New bounds on Poisson approximation to the distribution of a sum of negative binomial random variables [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2018
The Stein-Chen method is usedto give new bounds, non-uniform bounds, for the distances between the distribution of a sum of independent negative binomial random variables and a Poisson distribution with mean, where ri and pi = 1-qi are parameters of ...
Kanint Teerapabolarn
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

New Non-Uniform Lower Bounds for Uniform Classes.

open access: yes, 2016
We strengthen the nondeterministic hierarchy theorem for non-deterministic polynomial time to show that the lower bound holds against sub-linear advice. More formally, we show that for any constants d and d' such that 1 <= d < d', and for any time-constructible bound t=o(n^d), there is a language in NTIME(n^d) which is not in NTIME(t)/n^{1/d ...
Lance Fortnow, Rahul Santhanam
openaire   +4 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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