Results 111 to 120 of about 5,756,510 (243)

On Weyl's criterion for uniform distribution.

open access: yesMichigan Mathematical Journal, 1963
Es sei \(\{s_n (x)\}\) eine unendliche Folge von Funktionen, die auf einem Intervall \(a \leq x \leq b\) beschränkt und integrabel sind. \(S(N,x,m) = {1 \over N} \sum_{n=1}^N \exp (2 \pi i m s_n(x))\) (\(m\) ganz, \(\neq 0\)) seien die Weylschen Summen. Weiter sei \(I(N,m) = \int_a^b |S(N,x,m)|^2 \,dx\).
Davenport, H.   +2 more
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

How Uniform is the Uniform Distribution on Permutations?

open access: yes, 2019
For large $q$, does the (discrete) uniform distribution on the set of $q!$ permutations of the vector $(1,2,\dots,q)$ closely approximate the (continuous) uniform distribution on the $(q-2)$-sphere that contains them? These permutations comprise the vertices of the regular permutohedron, a $(q-1)$-dimensional convex polyhedron.
openaire   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

WLAN model with user movement trajectories with uniform user distribution.

open access: yes, 2015
WLAN model with user movement trajectories with uniform user distribution.
Insoo Sohn (704944)
core   +1 more source

Networks Based on Graphs of Transient Intensities and Product Theorems in Their Modelling

open access: yesComputation
This paper considers two models of queuing with a varying structure based on the introduction of additional transient intensities into known models or their combinations, which create stationary distributions convenient for calculation.
Gurami Tsitsiashvili
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

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