Results 101 to 110 of about 5,756,510 (243)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Limit Theorems for Empirical Processes Based on Dependent Data [PDF]

open access: yes
Empirical processes for non ergodic data are investigated under uniform distance. Some CLTs, both uniform and non uniform, are proved. In particular, conditions for Bn = n^(1/2) (µn - bn) and Cn = n^(1/2) (µn - an) to converge in distribution are given ...
Pietro Rigo   +2 more
core  

On the Maximum Probability of Full Rank of Random Matrices over Finite Fields

open access: yesMathematics
The problem of determining the conditions under which a random rectangular matrix is of full rank is a fundamental question in random matrix theory, with significant implications for coding theory, cryptography, and combinatorics. In this paper, we study
Marija Delić, Jelena Ivetić
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Enhancing Aluminum-Based Composite Manufacturing: Harnessing Si3N4 Reinforcement via Stir Casting Technique [PDF]

open access: yesE3S Web of Conferences
This study investigates the enhancement of aluminum-based composite manufacturing by incorporating Si3N4 reinforcement via the stir casting technique. Aluminum alloy serves as the matrix material, augmented with ceramic reinforcement particles. The alloy
Chahuan Neeraj   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Notes on the Distribution of Roots Modulo a Prime of a Polynomial V: Weyl’s Criterion

open access: yesMathematics
Let f(x) be a monic integral polynomial of degree n and p a prime number, for which f(x) is fully decomposable modulo p.
Yoshiyuki Kitaoka
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Local Linear Fitting Under Near Epoch Dependence: Uniform consistency with Convergence Rates [PDF]

open access: yes
Local linear fitting is a popular nonparametric method in statistical and econometric modelling. Lu and Linton (2007) established the pointwise asymptotic distribution for the local linear estimator of a nonparametric regression function under the ...
Zudi Lu, Degui Li, Oliver Linton
core  

Uniform/Benford mixture distribution results.

open access: yes, 2016
Simulated power for the tests and simultaneous confidence intervals when data are generated from the Uniform/Benford mixture distribution with various values of γ and for two sample sizes.
W. J. Reed (2577538)   +4 more
core   +1 more source

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